Biography:
Dr Isabelle Turbica is Assistant Professor in Biotechnology, at the School of Pharmacy of Paris-Saclay University since 2002, with skills that focus on therapeutic protein engineering and production. She is in charge of the Master degree “Pharmaceutical biotechnology and advanced therapies”. Her research field of interest deals with the immunogenicity of biotherapeutics, as she develops cellular models to assess the potential of aggregated therapeutic proteins to induce immune responses. She’s now interested in the description of cellular mechanisms involved in the activation of dendritic cells by the aggregates, along with the description of the switch towards adaptive immune responses, allowing the production of anti-drug antibodies.
Title : Immunogenicity of therapeutic antibodies: Role of aggregation in T lymphocyte response