Euro-Global Conference on Biotechnology and Bioengineering

September 06-08, 2021 | Online Event

September 06-08, 2021 | Online Event
ECBB 2021

Rosalinda Mazzei

Speaker at Biotechnology and Bioengineering 2021 - Rosalinda Mazzei
Institute on Membrane Technology CNR-ITM, Italy
Title : Biocatalytic membrane reactors towards process intensification in biocatalysis and biorefinery


Artificial membranes functionalized with biomolecules are very suitable for the development of biohybrid and biomimetic systems which find application in various fields. The system simulates the biological membrane compartmentalization, where the biological system can be heterogenized inside/on the membrane or simply retained by it and the substrate passage can be regulated by controlled fluid dynamic conditions. Despite the advantages of nature simulation these systems suffer of some issues, which need to be better studied in order to achieve a development on a large scale. The main problems are related to both biomolecule stability as well as membrane cleaning and re-use. In this keynote, an overview of the main application of biocatalytic membrane reactor in biocatalysis and biorefinery will be given together with the main drawbacks, which limits the development of this technology on larger scale. Innovative strategies to solve main problems related to membrane
stability/enzyme re-use will be described (eg. the use of biofunctionalized nanoparticles integrated with membrane for enzyme reuse). A deep understanding of biomolecule immobilization on membrane will be illustrated by using different biomolecule and functionalized membranes, to proof the concept of membrane versatility. Besides, a biocatalytic multiphasic intensified membrane system, able produce and stabilize in a single step phytotherapics will be also described, with the aim to provide alternative strategies for process intensification.


Researcher at CNR-ITM since 2011, degree in biology and PhD in vegetal physiology. Since 2003 she participated in various research projects funded by the EU, MIUR, CNR and private companies in the field of biorefinery, integrated membrane processes and membrane bioreactors. She serves as scientific and/or technical evaluator of research for funding institutions such as FONDECYT (Chile). She is co-author of 60 scientific papers published in international journals, more than 20 book chapters, various invited lectures and more than 100 contributions at scientific conferences on membrane science and engineering.