Euro-Global Conference on Biotechnology and Bioengineering

September 06-08, 2021 | Online Event

September 06-08, 2021 | Online Event
ECBB 2021

Jia Min

Speaker at Biotechnology and Bioengineering 2021 - Jia Min
Nanyang Technological University, Singapore
Title : The role of 3D printing and bioprinting in engineering a bioartificial pancreas for regenerative medicine in diabetes

Abstract:

The global rise in diabetes along with the current lack of sufficient donor human islets for cell replacement therapy motivates the making of a bioartificial pancreas to replace pancreas’ function. Technological advances in tissue engineering revolutionize diabetes treatment. One such technology is 3D printing and bioprinting. This computer-based fabrication process encourages innovation in bioengineering a bioartificial pancreas using a tri-factor approach – design, material, and processes. First, we highlight and compare different technologies available in 3D printing and bioprinting. The selection of suitable printing technology will enhance the fabrication process of bioartificial pancreas. Next, we identify key components of pancreas and clinical considerations for engineering a bioartificial pancreas. To recapitulate the pancreas’ function in insulin secretion and glycaemic control, the bioartificial pancreas will consist of three components 1. Cells (beta cells and supplementary cells) 2. Scaffold (for cell delivery) and 3. System (the housing of cells with scaffold). Thereafter, we match these needs and identify engineering solutions using 3D printing and bioprinting to mimic pancreas’ functionality. Lastly, we highlight challenges and potential directions towards an implantable bioartificial pancreas fabricated using 3D printing and bioprinting.

Biography:

Dr Lee Jia Min is currently a research fellow under the School of Mechanical & Aerospace Engineering, NTU. She is currently working on bioprinting and 3D printing for tissue engineering applications and alternative testing models. She has published over 18 articles, with 884 citations and has a H-index of 10. She has also filed 3 patent applications (2 SG provisional patent and 1 Non-drafted SG provisional patent) and 1 Know-how based on her Bioprinting and 3D Printing work. Her research interest includes, 3D Bioprinting, 3D Printing, Biosensors and Biotechnology.

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