Millions of people with diabetes suffer from the burden of daily subcutaneous insulin injections. Engineering a basal insulin for once weekly injection will result in fewer injections and likely improved acceptance of and compliance to the treatment, thereby improving glucose con [....] » Read More
Basic studies of the reactions in conventional neutralization tests without interference from complement and in complement-enriched neutralization tests were published in 1978 and 1982 [1,2]. The reaction in the conventional neutralization test was found to be bi-factorial, co [....] » Read More
MHC class I complexes can present antigenic peptides that have a sequence produced by post-translational mechanisms such as peptide splicing. Some examples of tumour-associated spliced epitopes have been investigated for their immunogenicity in the context of cancer so far. We de [....] » Read More
The research project involves studying the effect of addition of Maltogenic enzyme to improve the shelf life and other desirable properties of baking goods (white bread and tortillas). Maltogenic enzyme breaks down long chains of amylopectin in starch to shorter chains that can h [....] » Read More
The mass spectrometer (MS) is a versatile instrument suited for the analysis of biomolecules such as proteins, peptides, polysaccharides, small molecules/metabolites and nucleic acids. This presentation describes how MS-based approaches can be utilised for in-depth characterisati [....] » Read More
In the present study engineered cyanobacteria based biofertilizer using the concept of acclimatization and immobilization has been for the very first time introduced and attempted. The cyanobacterium Nostoc muscorum (N. muscorum) was well acclimatized to Al metal by initially sub [....] » Read More
Actinobacteria, a phylogenetically and metabolically diverse group of Gram-positive bacteria, have garnered substantial attention for their potential applications in sustainable agriculture, particularly as biopesticides. These microorganisms are prolific producers of secon [....] » Read More
Waste-derived biomass streams offer a promising resource for the cost-effective production of high value-added bioproducts in a circular bioeconomy. As part of the CBE project PROMOFER, this work outlines a comprehensive strategy to convert agro-industrial and lignocellulosic was [....] » Read More
Despite the rapid growth and innovation in biotechnology and pharmaceutical sectors, a persistent disconnect remains between academic training and the needs of industry. University curricula often equip students with the skills necessary for academic research but offer few struct [....] » Read More
Despite the rapid growth and innovation in biotechnology and pharmaceutical sectors, a persistent disconnect remains between academic training and the needs of industry. University curricula often equip students with the skills necessary for academic research but offer few struct [....] » Read More
Despite the rapid growth and innovation in biotechnology and pharmaceutical sectors, a persistent disconnect remains between academic training and the needs of industry. University curricula often equip students with the skills necessary for academic research but offer few struct [....] » Read More
Rising levels of global pollution pose significant threats to water and land ecosystems [1]. Accumulation of ammonia (NH4+) and nitrate (NO3-) in water lead to issues such as eutrophication and increased risks of colorectal cancer in humans and animals [2]. It is therefore crucia [....] » Read More
N-glycosylation, an asparagine-linked glycosylation process, plays a vital role in cellular interactions, angiogenesis, immune response, and effector functions. Altered N-glycosylation impacts tumor growth and both acute and chronic inflammatory processes. IgG, the second most ab [....] » Read More
DNA isolation is a crucial step in many molecular biological applications for diagnostic and research purposes. However, traditional extraction requires toxic reagents and commercially available kits are expensive, this leading to the recently wide-spread method, the magnetic nan [....] » Read More
Human cutaneous leishmaniasis (CL) is the disease caused by Leishmania sp. parasite and it endemic in Iraq and other world countries. This study comprised 78 cases of suspected CL disease. Before treatment, 66 (84.6%) cases were positive and 12 (15.4%) cases were negative among t [....] » Read More
Human cutaneous leishmaniasis (CL) is the disease caused by Leishmania sp. parasite and it endemic in Iraq and other world countries. This study comprised 78 cases of suspected CL disease. Before treatment, 66 (84.6%) cases were positive and 12 (15.4%) cases were negative among t [....] » Read More
Reactive, predictive musculoskeletal (MSK) models that integrate high-throughput proteomic, biomechanical, and physiological data offer a powerful tool for forecasting tissue adaptation under altered mechanical loading. Spaceflight—and its ground-based analogs such as roden [....] » Read More
Information Leakage threatens and questions the use of machine learning model in real-life clinical applications. In effect, information leakage is similar to vulgar overfitting, yet rather more subtle and even when detected much harder to remove. Some recent research indicates t [....] » Read More
At Total Potential Cells , anticipating the future is not enough; we believe in creating it. With traditional means of medicine falling short of the demands of the day, it is up to science and technology to provide solutions to the world's most pressing needs. Total Potential [....] » Read More
Implant infection is rising with the U.S. Centers for Disease Control predicting one person every three seconds will die from a bacteria infection by 2050. Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundr [....] » Read More
This study focuses on the development of an exosome delivery system, called Exo-ITC, with specific applications in dermatology. Exosomes are extracellular vesicles that play a crucial role in intercellular communication and hold great therapeutic potential in regenerative medicin [....] » Read More
Tissue and organ damage due to chronic diseases reduces the quality of life of an individual. Regenerative medicine, the field of research focused on repair, replacement or regeneration of cells, tissues and organs to restore impaired function. Approaches of regenerative therapy [....] » Read More
The biodiversity of animals in the ecosystem is important to balance the impact of environmental imbalance. In the paper, it discusses the methods and techniques of biotechnology that is being used to conserved and preserved exotic and endangered terrestrial and aquatic animals t [....] » Read More
Secondary metabolites produced from plants and microalgae are being used as food additives, flavors, and industrially important pharmaceuticals. The improved production of these metabolites through genetic engineering and use of phytohormones (elicitation) has unlocked a new area [....] » Read More
In order to shorten drug’s evolution time than personal cancer’s evolution time, a Tag-Tack platform was designed and constructed to make introcytoplastic missense proteins to be druggable in 6 months. We screened 8 human ScFVs for 6 introcytoplastic missense prote [....] » Read More
CytoNiche has developed 3D RecomTrix recombinant collagen dissolvable microcarriers for large-scale manufacturing of adherent cells, critical for allogeneic cell therapies like Mesenchymal Stem Cells (MSCs) and cell-free therapies like exosomes. The 3D FloTrix Technology integrat [....] » Read More
Understanding protein folding in vivo demands models that go beyond idealized, dilute conditions. The cellular environment is crowded, complex, and dynamically structured by intricate water networks. In this study, we employ large-scale atomistic simulations, powered by newly dev [....] » Read More
Salinity of soil is an emerging problem of agriculture that reduces plant growth. Salt affected soils are widely distributed throughout the world. Salinity is a presence of salt content in soil. Addition of salts, metals and xenobiotic chemicals to the soil severely reduce biogeo [....] » Read More
In the present study, bioconversion of glycerol using Gluconobacter oxydans NBRC 14819 to a high value-added product, Dihydroxyacetone (DHA), was examined with a perspective of medium optimization using One factor at a time (OFAT) approach. As per previous literature, glycerol, y [....] » Read More
In recent years, research focused on influenza prevention has led to the development of various vaccine formulations aimed at providing increasingly safe and effective products tailored for different age groups. This initiative seeks to optimize health outcomes, achieve economic [....] » Read More
This presentation concerns the investigation of micropolar magnetohydrodynamic (MHD) blood flows, with and without the effects of micromagnetorotation (MMR). MMR refers to the magnetic torque caused by the misalignment between the magnetization of magnetic particles in the fluid [....] » Read More
Excessive use of antibiotics as treatment or preventive agent, as well as growth promoters in animal husbandry, particularly in poultry farming, is one of the most important causes of the emergence of pathogenic bacteria that are increasingly resistant to antibiotics. In animals, [....] » Read More
Introduction: Ecological sanitation involves the use of hygienized human excreta as fertilizer in agriculture. This study aimed to establish the effects of hygienized urine and feces on cocoa production in the village of Blanfla in the Bouaflé Department of Côte d [....] » Read More
In the face of the growing threat of climate change and water scarcity, the cloning of economic importance native species superior phenotypes emerges as a strategic tool. Using this technique, a uniform, efficient propagation is guaranteed, selecting individuals with a higher res [....] » Read More
The Amazon Rainforest, a globally significant biodiversity hotspot, holds a vast and invaluable reservoir of plant genetic resources withimmense potential for innovative biotechnologicalapplications aligned with a sustainable bioeconomy. Despite its natural richness, much of this [....] » Read More
The lethal brain tumor “Glioblastoma” has the propensity to grow over time. To improve patient outcomes, it is essential to classify GBM accurately and promptly in order to provide a focused and individualized treatment plan. Despite this, deep learning methods, parti [....] » Read More
The tannery industry produces approximately 24 billion square feet of leather annually, with an estimated worth of $ 45 to $ 50 billion. It has a significant impact on the economies of developing countries, providing income and employment. This industry is tightly linked to agric [....] » Read More
