Title: Pharmacological profiling and molecular mechanism of biomolecules in anaerobic digestion slurry as alternative green therapy in cancer treatment and management
Biomolecules from organic materials dominate the green drug revolution in the 21st century. They are primarily extracts of plants and microorganisms accurately predicted with advances in computational biology. The over-exploration of medicinal plants and the need for new therapeutics, especially in cancer treatment, require the search for these essential biomolecules from cheap and readily available sources. Currently overlooked in drug discovery research, animal manure and anaerobic digestion slurry from biogas plants hold such potential. Therefore, the proposed study focuses on the pharmacological profiling of biomolecules formed in the biotransformation of organic slurry in the anaerobic digester as a potential therapeutic agent for cancer treatment. With the use of analytical, molecular and computational biology techniques, the findings will project the synthesis of a novel compound useful in cancer treatment or management. There is also a high potential for the discovery of biomolecules to treat other communicable and non-communicable diseases. The research will contribute to sustainable development goal 3 while addressing goals 7, 12 and 13 on the other.