Biofilm infections have no approved effective medical treatments and can only be disrupted via physical means. In this work, we describe a hybrid in silico laboratory pipeline for identifying and validating small-molecule inhibitors of RelA for use in the combinatorial [....] » Read More
The word “microbiota” refers to all the microorganisms that resides within human body. Several types of microbiota are associated with different district in our body and, in each of them, the mutualist interaction between the microorganisms and the host plays a critic [....] » Read More
Biosurfactants are amphipathic molecules that are synthesized by living cells with numerous potential applications in the areas of health and the environment, among others. However, the high production cost limits massive applications of biosurfactants. An interesting approach to [....] » Read More
Photoalignment and photopatterning has been proposed and studied for a long time [1]. Light is responsible for the delivery of energy as well as phase and polarization information to materials systems. It was shown that photoalignment liquid crystals by azodye nanolayers could pr [....] » Read More
Albumin is a plasma protein that maintains the oncotic pressure of the blood. It also acts as a carrier of lipophilic biomolecules like bilirubin. Recent research highlights that serum albumin exhibits various enzymatic functions apart from the aforementioned properties. Namely, [....] » Read More
Triple negative breast cancer (TNBC) is a particular breast cancer subtype, with the worse prognostic, characterised by the lack of expression of progesterone, estrogen and Her2 protein. Alterations of condign and non-coding genes were observed, a particular attention received s [....] » Read More
Background and objectives: Recent studies have witnessed the emergence end reemergence of SARS-CoV-2 variants leading to a succession of epidemic waves worldwide. The monitoring of SARS-CoV-2 variants in sewage is important for understanding the epidemic evolution and spread of C [....] » Read More
An obligate intracellular bacterium Orientia tsutsugamushi is the causative agent of a febrile disease, scrub typhus, which is endemic to Southeast Asia, including India, wherein there is a recent report on increased emergence of the disease in West Bengal state. The antibiotic t [....] » Read More
Liposomes are closed and spherical,l with one or more lipid bilayers, which form an internal cavity that can carry aqueous solutions. Llipid bilayers are composed of two sheets of tightly arranged phospholipids. The ability of liposomes to function as a drug delivery system can b [....] » Read More
Today Ayurveda science may be as advanced and authentic with perspective to gene editing or gene-therapy. In past years we find world is full of panicked with every word-goes starting with viruses, their all kind of mutants etc. Later on panicked continued with micro or nano pa [....] » Read More
Title : The hydrogen - based membrane biofilm reactor for reducing many oxidized contaminants
Bruce E Rittmann, Biodesign Swette Center for Environmental Biotechnology, United States
Among the most challenging water pollutants are those whose common characteristic is that they are chemically oxidized. The "classic" oxidized pollutants are nitrate and nitrite, and emerging oxidized pollutants include perchlorate, selenate, chromate, radionuclid [....] » Read More
Title : Brown recluse spider venom holds promise in killing breast cancer cells
Amy L Thompson, Austin Peay State University, United States
Brown recluse spiders, also known as Loxosceles reclusa, are endemic to the Southcentral United States. These spiders are known for their reclusive behavior and necrotic venom. Brown recluse bites can occasionally develop into dry wounds containing dead tissue or caus [....] » Read More
Title : Additive manufacturing of microbial polyesters for bone tissue engineering
Dario Puppi, University of Pisa, Italy
Polyhydroxyalkanoates (PHA)s are a class of aliphatic polyesters synthesized by various bacteria, with well-assessed biodegradability and biocompatibility. Their potential for large-scale sustainable production through microbial fermentation, together with superior processing ver [....] » Read More
Title : Post-transcriptional control in the regulation of polyhydroxy alkanoates synthesis
Alexandra Peregrina Lavin, NOVA University of Lisbon, Portugal
The large production of non-degradable petrol-based plastics has become a major global issue due to its environmental pollution. Biopolymers produced by microorganisms such as polyhydroxyalkanoates (PHAs) are gaining potential as a sustainable alternative, but the high cost assoc [....] » Read More
Title : Global warming due to biomaterials ?
Thomas J Webster, Interstellar Therapeutics, United States
Biomaterials are composed of some of the same materials as those used in non-medical applications (such as automobile, aerospace, consumer goods, etc.). While these other fields have moved away from using materials that are not environmentally friendly (such as those whic [....] » Read More
Title : The ecotechnlogy of modern ayurveda can effectively spoil all the evils, virions, microbes which are mere foreign-proteins can easily gets denaturated with plants’ acids (Ph < 6.5) or plants’ alkaloids (Ph > 8.0) for mankind
Debabrata Das, ICAR-CIFRI, India
Ecotechnlogy with modern Ayurveda can effectively spoil virions, microbes, mere foreign-proteins, unlike multi-cellular can easily get denatured with plants acids (ph < 6.5) or with plants alkaloids (ph > 8.0) study found in fisheries and mankind The very well f [....] » Read More
Title : ESKAPE pathogens in the Indian subcontinent: A comprehensive analysis
Aakanksha Kalra, Dr. B. Lal Institute of Biotechnology, Jaipur, India
ESKAPE pathogens are a group of antibiotic resistant gram positive and gram negative bacteria which are the causative agents for multiple nosocomial and community-acquired infections. ESKAPE refers to E. faecium, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, and Enteroba [....] » Read More