Albumin is a plasma protein that maintains the oncotic pressure of the blood. It also acts as a carrier of lipophilic biomolecules like bilirubin. Recent research highlights that serum albumin exhibits various enzymatic functions apart from the aforementioned properties. Namely, [....] » Read More
Triple negative breast cancer (TNBC) is a particular breast cancer subtype, with the worse prognostic, characterised by the lack of expression of progesterone, estrogen and Her2 protein. Alterations of condign and non-coding genes were observed, a particular attention received s [....] » Read More
Background and objectives: Recent studies have witnessed the emergence end reemergence of SARS-CoV-2 variants leading to a succession of epidemic waves worldwide. The monitoring of SARS-CoV-2 variants in sewage is important for understanding the epidemic evolution and spread of C [....] » Read More
An obligate intracellular bacterium Orientia tsutsugamushi is the causative agent of a febrile disease, scrub typhus, which is endemic to Southeast Asia, including India, wherein there is a recent report on increased emergence of the disease in West Bengal state. The antibiotic t [....] » Read More
Liposomes are closed and spherical,l with one or more lipid bilayers, which form an internal cavity that can carry aqueous solutions. Llipid bilayers are composed of two sheets of tightly arranged phospholipids. The ability of liposomes to function as a drug delivery system can b [....] » Read More
Today Ayurveda science may be as advanced and authentic with perspective to gene editing or gene-therapy. In past years we find world is full of panicked with every word-goes starting with viruses, their all kind of mutants etc. Later on panicked continued with micro or nano pa [....] » Read More
Biofilm infections have no approved effective medical treatments and can only be disrupted via physical means. In this work, we describe a hybrid in silico laboratory pipeline for identifying and validating small-molecule inhibitors of RelA for use in the combinatorial [....] » Read More
The word “microbiota” refers to all the microorganisms that resides within human body. Several types of microbiota are associated with different district in our body and, in each of them, the mutualist interaction between the microorganisms and the host plays a critic [....] » Read More
Biosurfactants are amphipathic molecules that are synthesized by living cells with numerous potential applications in the areas of health and the environment, among others. However, the high production cost limits massive applications of biosurfactants. An interesting approach to [....] » Read More
Photoalignment and photopatterning has been proposed and studied for a long time [1]. Light is responsible for the delivery of energy as well as phase and polarization information to materials systems. It was shown that photoalignment liquid crystals by azodye nanolayers could pr [....] » Read More
Heart rate variability (HRV) is defined as the temporary variation between heartbeats or RR intervals (distance between R waves in an electrocardiographic signal). This distance is currently a recognized biomarker. With the analysis of the distance, it is possible to assess the s [....] » Read More
Introduction: Masks need to be worn in pandemics, like the current COVID-19 pandemic. They have gained popularity and importance among people now. Face masks protect the non-exposed or susceptible persons from acquiring COVID-19, and also stop spread of the virus-laden aerosols f [....] » Read More
The coronavirus disease (COVID-19) pandemic, which is caused by an unique strain of coronavirus called severe acute respiratory syndrome corona virus 2 (SARS-CoV-2) virus infection, is one of the most important diseases in the current situation, according to the World Health Orga [....] » Read More
The study is on the brain tumour growth (glioblastoma), which is a very aggressive brain tumour. In this model, actually two parameters the diffusion and growth of tumour cells, have been focused. Based on various medical studies conducted by researchers, which demonstrate [....] » Read More
Microplastic pollution has become an environmental issue of great concern owing to the persistence of microplastics and their potential adverse effects on biota. Tiny plastic material with diameter <5mm is termed as microplastics or MPs, which can be classified into primary an [....] » Read More
Plastic leaking into the environment represents one of the major environmental concerns nowadays. Part of the solution is the replacement of conventional plastics with suitable biodegradable polymers. This especially useful in application where the items cannot be easily retrieve [....] » Read More
Incorporation of noncanonical amino acids (ncAA) into proteins has become an interesting topic as proteins featured with ncAAs offer a wide range of different applications. Nowadays, technologies and systems exist that allow for site-specific introduction of ncAAs in vivo, but th [....] » Read More
Candida albicans is opportunistic pathogen which causes life threatening disease candidiasis in living beings. Due to incessant use of antibiotics, the cure of candidiasis is problematic and need alternative medicine. Medicinal plants have been used to treat skin infection Since [....] » Read More
Will be Updated Soon...
Title : Global Warming Due to Biomaterials ?
Thomas J Webster , Interstellar Therapeutics, United States
Biomaterials are composed of some of the same materials as those used in non-medical applications (such as automobile, aerospace, consumer goods, etc.). While these other fields have moved away from using materials that are not environmentally friendly (such as those whic [....] » Read More
Title : The Ecotechnlogy Of Modern Ayurveda Can Effectively Spoil All The Evils, Virions, Microbes Which Are Mere Foreign-Proteins Can Easily Gets Denaturated With Plants’ Acids (Ph < 6.5) Or Plants’ Alkaloids (Ph > 8.0) For Mankind
Debabrata Das, ICAR-CIFRI, India
Ecotechnlogy with modern Ayurveda can effectively spoil virions, microbes, mere foreign-proteins, unlike multi-cellular can easily get denatured with plants acids (ph < 6.5) or with plants alkaloids (ph > 8.0) study found in fisheries and mankind The very well f [....] » Read More
Title : ESKAPE Pathogens in the Indian Subcontinent: A Comprehensive Analysis
Aakanksha Kalra, Dr. B. Lal Institute of Biotechnology, Jaipur, India
ESKAPE pathogens are a group of antibiotic resistant gram positive and gram negative bacteria which are the causative agents for multiple nosocomial and community-acquired infections. ESKAPE refers to E. faecium, S. aureus, K. pneumoniae, A. baumannii, P. aeruginosa, and Enteroba [....] » Read More
Title : The Hydrogen - Based Membrane Biofilm Reactor for Reducing Many Oxidized Contaminants
Bruce E Rittmann, Biodesign Swette Center for Environmental Biotechnology, United States
Among the most challenging water pollutants are those whose common characteristic is that they are chemically oxidized. The "classic" oxidized pollutants are nitrate and nitrite, and emerging oxidized pollutants include perchlorate, selenate, chromate, radionuclid [....] » Read More
Title : Brown Recluse Spider Venom Holds Promise in Killing Breast Cancer Cells
Amy L Thompson, Austin Peay State University, United States
Brown recluse spiders, also known as Loxosceles reclusa, are endemic to the Southcentral United States. These spiders are known for their reclusive behavior and necrotic venom. Brown recluse bites can occasionally develop into dry wounds containing dead tissue or caus [....] » Read More
Title : Additive Manufacturing of Microbial Polyesters for Bone Tissue Engineering
Dario Puppi, University of Pisa, Italy
Polyhydroxyalkanoates (PHA)s are a class of aliphatic polyesters synthesized by various bacteria, with well-assessed biodegradability and biocompatibility. Their potential for large-scale sustainable production through microbial fermentation, together with superior processing ver [....] » Read More
Title : Post-Transcriptional Control in the Regulation of Polyhydroxyalkanoates Synthesis
Alexandra Peregrina Lavin, NOVA University of Lisbon, Portugal
The large production of non-degradable petrol-based plastics has become a major global issue due to its environmental pollution. Biopolymers produced by microorganisms such as polyhydroxyalkanoates (PHAs) are gaining potential as a sustainable alternative, but the high cost assoc [....] » Read More
Title : Lactococcus lactis, a promising cell factory to functionally express membrane proteins
Frelet Barrand Annie, Institute FEMTO, France
Membrane proteins (MPs) play key roles in most crucial cellular processes ranging from cell to cell communication to signaling processes. Despite recent improvements, the expression of functionally folded membrane proteins in sufficient amounts for their functional and structural [....] » Read More
Title : Combinatorial fusion tag yields powerful platform process for the production of pharmaceutically relevant proteins
Christoph Koppl, Austrian Centre of Industrial Biotechnology GmbH, Austria
Expression of complex recombinant proteins in E. coli is a major challenge in industrial biotechnology as the protein of interest is often produced with very low titres or misfolded as inclusion body. One possibility to circumvent these problems is the use of fusion partners. Unf [....] » Read More
Title : Differentiating Alpha Beta 40 and Alpha Beta 42 in amyloid plaques with a small molecule fluorescence probe
Biyue Zhu, Massachusetts general hospital, United States
Differentiating amyloid beta (Aβ) subspecies Aβ40 and Aβ42 has long been considered an impossible mission with small-molecule probes. In this report, based on recently published structures of Aβ fibrils, we designed iminocoumarin–thiazole (ICT) fluores [....] » Read More
Title : Embedded-microstructures arrays for single-cell sorting and collecting of lymphocytes following HIV latency reactivation
Belen Cortes Llanos , Duke University , United States
The study of single cells has recently accelerated in many fields, oncology, neuroscience, virology, and immunology, among others.Bulk studies provided excellent knowledge, but much information was lost when collecting data from cell populations. Different cell-separation platfor [....] » Read More
Title : Chitosan-based Polyelectrolyte Complex Hydrogels by Additive Manufacturing for 3D In Vitro Cancer Modelling
Simona Braccini, University of Pisa, Italy
Polymeric hydrogels have been used over the past two decades as one of the most common types of tissue engineering scaffold thanks to their ability to maintain a distinct 3D structure in physiological environment, offer structural support for cells in the engineered tissues, and [....] » Read More
Title : CRISPR/Cas9 system in the generation of genetically modified pigs for purpose of xenotransplantation
Magdalena Hryhorowicz, Poznan University of Life , Poland
CRISPR/Cas (clustered regularly interspaced short palindromic repeats, CRISPR; CRISPR-associated proteins, Cas) system has revolutionized of genetic engineering research and animal biotechnology. Introducing precise modifications in a specific site of the genome is possible due t [....] » Read More
Title : Towards Automated Decision-Making Through Reinforcement Learning
Borja G Leon, Imperial College London, United Kingdom
Artificial intelligence (AI) holds considerable promise to tackle challenging decision-making problems such as automated health testing and drug discovery. Among the different AI paradigms, reinforcement learning (RL), a technique that concerns autonomous agents interacting with [....] » Read More
Title : Pharmacological profiling and molecular mechanism of biomolecules in anaerobic digestion slurry as alternative green therapy in cancer treatment and management
Olaniyan Oluwaiey Paul, Osun State University, Nigeria
Biomolecules from organic materials dominate the green drug revolution in the 21st century. They are primarily extracts of plants and microorganisms accurately predicted with advances in computational biology. The over-exploration of medicinal plants and the need for new therapeu [....] » Read More
Title : Exploration of mycoviruses from Trichoderma spp. in China
Beilei Wu, Chinese Academy of Agricultural sciences , China
The mycovirus is the research hot in recent years. Until now, seven isolates were explored from Inner Mongolia and Xinjiang provinces in China. They mediated the host (Trichoderma spp.) have the functions of enchancing the growth of plant and improving the capability of [....] » Read More
Title : Low-cost and Efficient Biobased Material For Removal Of Noble Metals In Gold Tailing Dam
Ruben Dario Sinisterra, Federal University of Minas Gerais, Brazil
The technological advance of the industry is an important factor in the increase of environmental pollution by industrial effluents, since high amounts of chemical load, metals, toxic and highly dangerous elements are produced. In Brazil, mining in its mineral processing generate [....] » Read More
Title : Augmented whole-cell biotransformation of the toxic 3-chloropropiophenone into 1-phenyl-1-propanone by microalgae Chlorella emersonii immobilized in hydrogel
Francesco Secundo, Istituto di Scienze e Tecnologie Chimiche "Giulio Natta", Italy
Dehalogenation of halogenated organic substrate (3-Chloropropiophenone, 3-CPP) is conducted using whole cells microalgae Chlorella emersonii (211.8b) as biocatalyst. C. emersonii cells were immobilized by entrapment (without any covalent bonds) in Aquasorb (an anionic polyacrylat [....] » Read More
Title : Bacteriophage based biocontrol of drug-resistant Enterobacter cloacae
Aparna Nair, CSIR-National Environmental Engineering Research Institute, India
The global emergence of multi-drug resistant Enterobacter cloacae complex is one of the critical threats faced today by health care system as indicated by World Health Organisation. Enterobacter cloacae is one of the most common Enterobacter species amongst the E. cloacae complex [....] » Read More