Sebastian Oltean, University of Exeter Medical School, United Kingdom
Alternative splicing is known to occur in more than 94% if genes in humans. Cancers express specific splice isoforms, or the normal ratios of isoforms are disrupted. While some of these events may be just a silent by-product of the cancer progression, many of them have functional [....] » Read More
Title : Pressure plate analysis in musculoskeletal injuries: An overview
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal injuries are extremely common in both humans and Animals. The prevalence of musculoskeletal injuries has increased due to a number of variables, such as decreasing physical activity, higher life expectancy, and professional athleticism. Joint deterioration is a fr [....] » Read More
Title : Biotech scale-up: Bioengineering imperatives in biomanufacturing
Murray Moo Young, University of Waterloo, Canada
During the recent pandemic, it became clear that the main deterrence of manufacturing of newly discovered vaccines was the implementation of prerequisite bioreactor design, operation and control for commercial production. The range of imperatives for success can be wide and compl [....] » Read More
Title : Immunogenicity of therapeutic antibodies: Role of aggregation in T lymphocyte response
Isabelle Turbica, Paris Saclay University, France
Immunogenicity has been described as a major concern to the clinical use of therapeutic antibodies, as treated patients frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response. Among other factors, it is now well a [....] » Read More
Title : Ursodeoxycholic acid is associated with better clinical outcome in COVID - 19 patients: A population based cohort study
Jong Seung Kim, Jeonbuk National University Medical School, Korea, Republic of
Background: Several studies have investigated the relationship between ursodeoxycholic acid (UDCA) and coronavirus disease 2019 (COVID-19). However, complex and conflicting results have caused confusion in the application of these results. We aimed to investigate whether the asso [....] » Read More
Title : The scale-up and culturability of live biotherapeutics for reproductive health in South Africa
Obakeng Jona, University of Cape Town, South Africa
Bacterial vaginosis is a highly prevalent inflammatory condition, characterised by the absence of protective. Lactobacillaceae commensal species and their replacement by vaginal pathogens such as Gardnerella vaginalis. It is known to increase HIV infection rates and thus presents [....] » Read More
Title : Valorization of wastes via a one-step microbial fermentation process
Fernando Santos Beneit, University of Valladolid, Spain
Pollution from plastic waste represents one of the most relevant environmental problems that our society currently faces. Most conventional plastics are extremely recalcitrant, with estimated decomposition times of decades to centuries. However, the production of plastics increas [....] » Read More
Title : The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction
Youngwook Ham, Korea Research Insitute of Bioscience and Biotechnology, Korea, Republic of
The COVID-19 pandemic is an ongoing global public health threat. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and binding of the SARS-CoV-2 spike to its receptor, angiotensin-converting enzyme 2 (ACE2), on host cells is critical fo [....] » Read More
Title : Production of hydroxyectoine with an engineered strain of Methylomicrobium alcaliphilum
Sergio Bordel, University of Valladolid, Spain
Methylomicrobium alcaliphilum is a halotolerant methanotroph, which produces ectoine under high salinity conditions. Ectoine is an osmoprotector and protein stabilizer that allows microorganisms to survive at high salt concentrations (up to 9% in the case of M. alcaliphilum) and [....] » Read More
Title : Fabrication of symbiotic multicellular assemblies by using a novel “Gel Layer-by-Gel Layer” technique
Reem Alhaidose, Ministry Of Municipality - Biotech Center, Qatar
The research on biofilms has skyrocketed in recent years due to increased awareness of the pervasiveness and impact of biofilms on natural and industrial systems, as well as human health. A biofilm is a well-organized, cooperating community of microorganisms. Microbial cells atta [....] » Read More