Alternative splicing is known to occur in more than 94% if genes in humans. Cancers express specific splice isoforms, or the normal ratios of isoforms are disrupted. While some of these events may be just a silent by-product of the cancer progression, many of them have functional [....] » Read More
Pretilachlor is a systemic, pre-emergence herbicide applied in the paddy fields to kill narrow and broadleaf weeds. The present study evaluates the toxicity of pretilachlor on the non-target diazotrophic free-living cyanobacterium Anabaena doliolum, commonly found in the paddy fi [....] » Read More
The adhesive structures of marine mussel plaques have attracted significant attention owing to their remarkable adhesive properties. In this paper, we experimentally investigated the three-dimensional (3D) responses of marine mussel plaques anchoring to wet polydimethylsiloxane ( [....] » Read More
Cordyceps spp., a mushroom species that parasitizes and grows on insects, has long been used as a herbal medicine. One of its active ingredients, cordycepin, is an analog of adenosine. It is a promising raw material for pharmaceuticals and cosmetics due to its known biological ac [....] » Read More
The production efficiency has an important role for each manufacturing process, especially in the process of drilling a large number of holes, where production depends on the time required for drilling. The tool path optimization during the drilling is necessary because it leads [....] » Read More
Nanoparticular drug delivery is widely studied system to transport a broad range of synthetic drugs, bio-molecules, and natural compounds into the body. However, constant intake of the occupational dose of mineral-rich dust is dangerous, often leading to one of the diseases such [....] » Read More
Cardiovascular diseases are increasingly prevalent globally, with thrombosis being a major contributor. Current thrombolytic drugs, while effective, are associated with significant side effects, including immune responses, haemorrhages, and stability issues. In contrast, microbia [....] » Read More
Sexing by gene editing in pigs is an alluring alternative to the surgical castration of piglets as the male-specific boar taint remains a major obstacle in pork production. In mice, the SRY-gene was first described as a genetic developmental switch for the male phenotype. Th [....] » Read More
Today, more and more attempts are being made to apply the circular economy model, to overcome the linear economy model, also favouring green and ecological industrial and chemical processes. As a result, molecules from the plant world are becoming increasingly relevant and attemp [....] » Read More
Mycoremediation has become an important approach for managing heavy metal pollution. Cadmium (Cd) is a well-known global contaminant, listed among the most hazardous inorganic substances, but there are few reports about its remediation by mangrove fungi, the highly potential [....] » Read More
Outcomes of anticancer therapy vary dramatically among patients, which may be caused by the specific molecular alterations in each patient’s tumor. The development of ex vivo drug test-guided clinical response prediction platform has elicited clinical and industrial interes [....] » Read More
Puberty in teleost is characterized by the development and maturation of the gonads. It is a multifaceted complex process and involves different molecules, for instance, it is now known that Kisspeptin a key upstream regulator of the Hypothalamus-Pituitary-Gonadal axis (HPG) whic [....] » Read More
The Arabian Gulf surrounding Qatar is distinct from other marine ecosystems due to its high salinity, limited rainfall, extreme water temperature fluctuations and furthermore, in the last decade, Qatar has been witnessing an industrial boom as well as extensive infrastructure con [....] » Read More
Background and Purpose: Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma arising from the epithelial lining of the nasopharynx. Inflammation has significant effects on the prognosis of NPC patients. The inflammatory reaction stimulated by cancer is beneficial to its g [....] » Read More
Consider the problem of assessing the success of a treatment A and treatment B in cancer patients. The response variable is Y, the patient’s survival in days, and the clinicopathological variables are age, sex, gene expression, and so on. Such data is often censored, meanin [....] » Read More
Traditional wound dressings historically served to clean, shield, and safeguard wounds from external factors. However, the right dressing choice can expedite healing, provide cost-effective care, and enhance a patient's well-being. Electrospun fibers, renowned for their varie [....] » Read More
Artificial intelligence (AI) has already revolutionized numerous industries, yet, its use in nanotechnology and biomaterials is almost non-existent. This invited presentation will provide a summary of how AI can be used to design better biomaterials for various biomedical applica [....] » Read More
miRNAs are noncoding RNAs that regulate gene expression, inducing degradation or translational repression of mRNA. They are functionally involved in the process of carcinogenesis such as cell differentiation, proliferation, and apoptosis. However, it is important to keep in mind [....] » Read More
By 2050, it is expected that there will be 9.7 billion people on the planet, which would provide a serious threat to food security. The increasing need for food has made traditional agricultural practices insufficient, so innovative technology must be adopted to increase producti [....] » Read More
With the advent of Artificial Intelligence in all facets of life, the advent of AI based Clinical psychologist robot and NLP chatbot simulating actual Clinical psychologist that would talk to patient in their own mother tongue and counselling can be taken as and when required. Be [....] » Read More
Municipal organic solid waste is a rich source of carbohydrates, proteins, fats and lignocellulosic waste which provides an environment for the growth of different waste decomposing microbes. In Indian scenario huge amount of waste is being generated per day. It becomes a huge en [....] » Read More
Ecotoxicological investigations often subject test organisms to optimal environmental conditions. However, these organisms rarely encounter such ideal circumstances in their natural habitats. Instead, they typically contend with sub-optimal conditions and periodic exposure to env [....] » Read More
Microfluidic Phase separation exploits the manipulation of fluid flow and the interaction of different phases to isolate and concentrate the target analytes from complex biological samples. In this paper, we review the recent progress in phase separation microfluidics for allergy [....] » Read More
Microfluidic Phase separation exploits the manipulation of fluid flow and the interaction of different phases to isolate and concentrate the target analytes from complex biological samples. In this paper, we review the recent progress in phase separation microfluidics for allergy [....] » Read More
Human cutaneous leishmaniasis (CL) is the disease caused by Leishmania sp. parasite and it endemic in Iraq and other world countries. This study comprised 78 cases of suspected CL disease. Before treatment, 66 (84.6%) cases were positive and 12 (15.4%) cases were negative among t [....] » Read More
The research work includes the transcriptome analysis of tomato genotypes viz., AT-3 (S. lycopersicum), SL 12s0 (S. lycopersicum), LA 1777 (S. habrochaites) and LA 2157 (S. arcanum) under nematode, M. incognita (nematode) stress. The sequencing was done on the Illumina MiSeq plat [....] » Read More
In the biopharmaceutical industry, the quest for approaches to accelerate the generation of high-producing cell lines has always been challenging and crucial. In this regard, exploring novel techniques and combining them can assist in achieving this objective. One of the most cha [....] » Read More
Pigeonpea is an often cross-pollinated grain legume with high nutritional value making it an important blend in a cereal-dominated diet. It is an annual diploid (2n=22) with a typical 9+1 diadelphous stamen in a chasmogamous flower which opens before fertilization often leading t [....] » Read More
To analyze the relationship between the expression of serum microRNA (miR) -202 and miR-34a and nosocomial infection after transcatheter arterial chemoembolization (TACE) in patients with primary liver cancer. Methods: A total of 125 patients with primary liver cancer who unde [....] » Read More
Title : Pressure plate analysis in musculoskeletal injuries: An overview
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal injuries are extremely common in both humans and Animals. The prevalence of musculoskeletal injuries has increased due to a number of variables, such as decreasing physical activity, higher life expectancy, and professional athleticism. Joint deterioration is a fr [....] » Read More
Title : Biotech scale-up: Bioengineering imperatives in biomanufacturing
Murray Moo Young, University of Waterloo, Canada
During the recent pandemic, it became clear that the main deterrence of manufacturing of newly discovered vaccines was the implementation of prerequisite bioreactor design, operation and control for commercial production. The range of imperatives for success can be wide and compl [....] » Read More
Title : Immunogenicity of therapeutic antibodies: Role of aggregation in T lymphocyte response
Isabelle Turbica, Paris Saclay University, France
Immunogenicity has been described as a major concern to the clinical use of therapeutic antibodies, as treated patients frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response. Among other factors, it is now well a [....] » Read More
Title : Ursodeoxycholic acid is associated with better clinical outcome in COVID - 19 patients: A population based cohort study
Jong Seung Kim, Jeonbuk National University Medical School, Korea, Republic of
Background: Several studies have investigated the relationship between ursodeoxycholic acid (UDCA) and coronavirus disease 2019 (COVID-19). However, complex and conflicting results have caused confusion in the application of these results. We aimed to investigate whether the asso [....] » Read More
Title : The scale-up and culturability of live biotherapeutics for reproductive health in South Africa
Obakeng Jona, University of Cape Town, South Africa
Bacterial vaginosis is a highly prevalent inflammatory condition, characterised by the absence of protective. Lactobacillaceae commensal species and their replacement by vaginal pathogens such as Gardnerella vaginalis. It is known to increase HIV infection rates and thus presents [....] » Read More
Title : Valorization of wastes via a one-step microbial fermentation process
Fernando Santos Beneit, University of Valladolid, Spain
Pollution from plastic waste represents one of the most relevant environmental problems that our society currently faces. Most conventional plastics are extremely recalcitrant, with estimated decomposition times of decades to centuries. However, the production of plastics increas [....] » Read More
Title : The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction
Youngwook Ham, Korea Research Insitute of Bioscience and Biotechnology, Korea, Republic of
The COVID-19 pandemic is an ongoing global public health threat. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and binding of the SARS-CoV-2 spike to its receptor, angiotensin-converting enzyme 2 (ACE2), on host cells is critical fo [....] » Read More
Title : Production of hydroxyectoine with an engineered strain of Methylomicrobium alcaliphilum
Sergio Bordel, University of Valladolid, Spain
Methylomicrobium alcaliphilum is a halotolerant methanotroph, which produces ectoine under high salinity conditions. Ectoine is an osmoprotector and protein stabilizer that allows microorganisms to survive at high salt concentrations (up to 9% in the case of M. alcaliphilum) and [....] » Read More
Title : Fabrication of symbiotic multicellular assemblies by using a novel “Gel Layer-by-Gel Layer” technique
Reem Alhaidose, Ministry Of Municipality - Biotech Center, Qatar
The research on biofilms has skyrocketed in recent years due to increased awareness of the pervasiveness and impact of biofilms on natural and industrial systems, as well as human health. A biofilm is a well-organized, cooperating community of microorganisms. Microbial cells atta [....] » Read More