Alternative splicing is known to occur in more than 94% if genes in humans. Cancers express specific splice isoforms, or the normal ratios of isoforms are disrupted. While some of these events may be just a silent by-product of the cancer progression, many of them have functional [....] » Read More
Pretilachlor is a systemic, pre-emergence herbicide applied in the paddy fields to kill narrow and broadleaf weeds. The present study evaluates the toxicity of pretilachlor on the non-target diazotrophic free-living cyanobacterium Anabaena doliolum, commonly found in the paddy fi [....] » Read More
The adhesive structures of marine mussel plaques have attracted significant attention owing to their remarkable adhesive properties. In this paper, we experimentally investigated the three-dimensional (3D) responses of marine mussel plaques anchoring to wet polydimethylsiloxane ( [....] » Read More
Cordyceps spp., a mushroom species that parasitizes and grows on insects, has long been used as a herbal medicine. One of its active ingredients, cordycepin, is an analog of adenosine. It is a promising raw material for pharmaceuticals and cosmetics due to its known biological ac [....] » Read More
The production efficiency has an important role for each manufacturing process, especially in the process of drilling a large number of holes, where production depends on the time required for drilling. The tool path optimization during the drilling is necessary because it leads [....] » Read More
Nanoparticular drug delivery is widely studied system to transport a broad range of synthetic drugs, bio-molecules, and natural compounds into the body. However, constant intake of the occupational dose of mineral-rich dust is dangerous, often leading to one of the diseases such [....] » Read More
Conventional plastics have improved humanity in many ways since they were invented, but there is no denying that they have an adverse impact on living things and natural environments. The search for plastic substitutes, or bioplastics, is essential since the management of plastic [....] » Read More
The placement of Titanium implants has become an attractive method for the bone regeneration process. However, the poor osteointegration effects lead to poor cellularization which opens the gateway for novel biocompatible coating. Using these findings here in this work we have pr [....] » Read More
Plastic has detrimental effects on environment, animal, and human health, due to its non-biodegradable nature. Bioplastic, an environment friendly material, can be derived from biologically renewable resources. Research is now focused on developing biodegradable bioplastic due to [....] » Read More
Cardiovascular diseases are increasingly prevalent globally, with thrombosis being a major contributor. Current thrombolytic drugs, while effective, are associated with significant side effects, including immune responses, haemorrhages, and stability issues. In contrast, microbia [....] » Read More
Anaemia and vitamin A deficiency in children and pregnant women are a public health problem in Cameroon. The Cameroon government, with the support of the WHO and UNICEF, is helping to combat these deficiencies by giving vitamin A supplements to children and pregnant and breastfee [....] » Read More
Sexing by gene editing in pigs is an alluring alternative to the surgical castration of piglets as the male-specific boar taint remains a major obstacle in pork production. In mice, the SRY-gene was first described as a genetic developmental switch for the male phenotype. Th [....] » Read More
Today, more and more attempts are being made to apply the circular economy model, to overcome the linear economy model, also favouring green and ecological industrial and chemical processes. As a result, molecules from the plant world are becoming increasingly relevant and attemp [....] » Read More
Mycoremediation has become an important approach for managing heavy metal pollution. Cadmium (Cd) is a well-known global contaminant, listed among the most hazardous inorganic substances, but there are few reports about its remediation by mangrove fungi, the highly potential [....] » Read More
The most important problem in the gene therapy is gene delivery. Cell-penetrating peptides (CPPs) have emerged as versatile tools for delivering various cargoes into cells. However, the exact mechanism of cellular uptake by CPPs remains elusive. This study aimed to explore the ef [....] » Read More
Photoalignment and photopatterning has been deproposed and studied for a long time [1]. Light is responsible for the delivery of energy as well as phase and polarization information to materials systems. It was shown that photoalignment liquid crystals by azodye nanolayers could [....] » Read More
Remodeling eubiosis of the gut microenvironment may contribute to preventing the occurrence and development of depression. Mounting experimental evidence has shown that complement C3 signaling is associated with the pathogenesis of depression, and disruption of the gut microbiota [....] » Read More
Outcomes of anticancer therapy vary dramatically among patients, which may be caused by the specific molecular alterations in each patient’s tumor. The development of ex vivo drug test-guided clinical response prediction platform has elicited clinical and industrial interes [....] » Read More
Introduction: HBV infection is the tenth leading cause of death worldwide, accounting for between 580,000 and 1.2 million deaths per year and approximately 8% of all HBV carriers worldwide are co-infected with the virus hepatitis delta (HDV). In Africa, about a quarter of the 68 [....] » Read More
Puberty in teleost is characterized by the development and maturation of the gonads. It is a multifaceted complex process and involves different molecules, for instance, it is now known that Kisspeptin a key upstream regulator of the Hypothalamus-Pituitary-Gonadal axis (HPG) whic [....] » Read More
My paper endeavours to delve into the pertinent influences of biotechnology that can be used toescalate bio conservation practices. Biotechnology can be used to tackle environmental issues like deforestation and air pollution. Biotechnology can help in finding out the level of Pa [....] » Read More
Hydrogen is the most essential gas that can be used for many purposes. During the production of hydrogen using raw materials like Soil and leftover cooked rice water (kanjivellam) the major by-product formed is water. Soil is collected from three different places in kottayam dist [....] » Read More
The exploitation of Manganese in Moanda in the South-East of Gabon leads to the discharge of mining residues into the soil (Mokéa-Niaty, 2019) . The market gardening activities that are developing there expose the populations to the risks of the transfer of metal pollutant [....] » Read More
GLP-1, an incretin hormone, targets the G protein-coupled receptor GLP-1R, expressed in brain regions crucial for regulating food intake and satiety, particularly in the hypothalamus. Recently, two long-acting peptide GLP-1R agonists (GLP1RAs), liraglutide and semaglutide, were a [....] » Read More
The Arabian Gulf surrounding Qatar is distinct from other marine ecosystems due to its high salinity, limited rainfall, extreme water temperature fluctuations and furthermore, in the last decade, Qatar has been witnessing an industrial boom as well as extensive infrastructure con [....] » Read More
Background and Purpose: Nasopharyngeal carcinoma (NPC) is a squamous cell carcinoma arising from the epithelial lining of the nasopharynx. Inflammation has significant effects on the prognosis of NPC patients. The inflammatory reaction stimulated by cancer is beneficial to its g [....] » Read More
Consider the problem of assessing the success of a treatment A and treatment B in cancer patients. The response variable is Y, the patient’s survival in days, and the clinicopathological variables are age, sex, gene expression, and so on. Such data is often censored, meanin [....] » Read More
Traditional wound dressings historically served to clean, shield, and safeguard wounds from external factors. However, the right dressing choice can expedite healing, provide cost-effective care, and enhance a patient's well-being. Electrospun fibers, renowned for their varie [....] » Read More
Artificial intelligence (AI) has already revolutionized numerous industries, yet, its use in nanotechnology and biomaterials is almost non-existent. This invited presentation will provide a summary of how AI can be used to design better biomaterials for various biomedical applica [....] » Read More
miRNAs are noncoding RNAs that regulate gene expression, inducing degradation or translational repression of mRNA. They are functionally involved in the process of carcinogenesis such as cell differentiation, proliferation, and apoptosis. However, it is important to keep in mind [....] » Read More
Antithrombin III is an important anticoagulant factor with anti-inflammatory properties. However, few studies have explored its anti-inflammatory actions in ATIII overexpressed transgenic animals. In this study, the dairy goats with mammary overexpression of ATIII were used to in [....] » Read More
By 2050, it is expected that there will be 9.7 billion people on the planet, which would provide a serious threat to food security. The increasing need for food has made traditional agricultural practices insufficient, so innovative technology must be adopted to increase producti [....] » Read More
With the advent of Artificial Intelligence in all facets of life, the advent of AI based Clinical psychologist robot and NLP chatbot simulating actual Clinical psychologist that would talk to patient in their own mother tongue and counselling can be taken as and when required. Be [....] » Read More
Municipal organic solid waste is a rich source of carbohydrates, proteins, fats and lignocellulosic waste which provides an environment for the growth of different waste decomposing microbes. In Indian scenario huge amount of waste is being generated per day. It becomes a huge en [....] » Read More
Ecotoxicological investigations often subject test organisms to optimal environmental conditions. However, these organisms rarely encounter such ideal circumstances in their natural habitats. Instead, they typically contend with sub-optimal conditions and periodic exposure to env [....] » Read More
Microfluidic Phase separation exploits the manipulation of fluid flow and the interaction of different phases to isolate and concentrate the target analytes from complex biological samples. In this paper, we review the recent progress in phase separation microfluidics for allergy [....] » Read More
Microfluidic Phase separation exploits the manipulation of fluid flow and the interaction of different phases to isolate and concentrate the target analytes from complex biological samples. In this paper, we review the recent progress in phase separation microfluidics for allergy [....] » Read More
No one has scientifically proven that antipyretic therapy, which reduces the heat of a fever, is an appropriate treatment for fever and inflammation. Conflicting opinions on the effectiveness of various antipyretic treatments can be found in various journals. Here we consider the [....] » Read More
Breast cancer remains one of the most prevalent malignancies worldwide, with limited treatment options available for aggressive subtypes such as triple-negative breast cancer (TNBC). The high recurrence rates and resistance to conventional therapies necessitate the exploration of [....] » Read More
Subject description: Faidherbia albida is a species that loses its leaves during the rainy season, unlike other savannah plants Objective: The aim of this study was to assess phytohormone levels in the plant's aerial organs during the hot, humid period Method: Phenologi [....] » Read More
Cancer is undoubtedly one of the most prevalent and lethal diseases in this day and age. So, early diagnosis and treatment of this disease are of paramount importance, drawing the attention of researchers and scientists worldwide. Among various methods of diagnosis, Raman spectro [....] » Read More
Human cutaneous leishmaniasis (CL) is the disease caused by Leishmania sp. parasite and it endemic in Iraq and other world countries. This study comprised 78 cases of suspected CL disease. Before treatment, 66 (84.6%) cases were positive and 12 (15.4%) cases were negative among t [....] » Read More
Mutations in GDAP 1 (Ganglioside induced differentiation associated protein 1) are linked with CMT (Charcot Marie Tooth), a type of peripheral neuropathy. GDAP1 mutations are the cause of CMT disease and proved to be associated with vocal cord palsy and diaphragmatic dysfun [....] » Read More
Will be Updated Soon...
Zebrafish larva is a simple model system to study blood vessel development because of its excellent optical properties. Current methods to study blood vessels in zebrafish involve utilizing either blood vessel-specific transgenic lines or specialized techniques such as microangio [....] » Read More
Research into alternate ethanol production pathways has been spurred by the need for sustainable energy sources, and lignocellulosic biomass has emerged as a viable feedstock. An integrated method that includes pre-treatment, fermentation, distillation, and enzymatic hydrolysis i [....] » Read More
The presence of medicinal plants is controlled by time and seasons, which requires their conservation, in order to expand their use during the year, as well as their storage and marketing. Our main objective is to study the effect of some conservation methods on garlic, which is [....] » Read More
The objective of this study was to determine the effect of Azolla filiculoides on the growth parameters of rice Wita 9 and zootechnics tilapia Oreochromis niloticus in a rice-fish culture. Fingerlings (6.11 ± 0.19 g; 12 fingerlings/m²) were placed in the ponds transpl [....] » Read More
The orange-yellow essential oil with a yield of 1.54 % was extracted from the dry leaves of Cymbopogon citratus (DC.) Stapf harvested south of Brazzaville. Analysis by gas chromatography (GPC) and gas chromatography coupled with mass spectrometry (GPC/MS) allowed the identificati [....] » Read More
Pigeonpea is an often cross-pollinated grain legume with high nutritional value making it an important blend in a cereal-dominated diet. It is an annual diploid (2n=22) with a typical 9+1 diadelphous stamen in a chasmogamous flower which opens before fertilization often leading t [....] » Read More
Animal testing has become essential for preclinical screening in the drug discovery process, but there are still several problems, including ethical concerns and species disparities. The use of grown cells for testing drugs' effects and cytotoxicity has become commonplace as [....] » Read More
The mitochondrial disease often associated with various illnesses in relation to the activity of cells metabolites and the synthesis of adenosine triphosphate (ATP). Leigh syndrome part of a continuum of progressive neurodegenerative disorders caused by abnormalities of mitochond [....] » Read More
To analyze the relationship between the expression of serum microRNA (miR) -202 and miR-34a and nosocomial infection after transcatheter arterial chemoembolization (TACE) in patients with primary liver cancer. Methods: A total of 125 patients with primary liver cancer who unde [....] » Read More
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Title : Pressure plate analysis in musculoskeletal injuries: An overview
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal injuries are extremely common in both humans and Animals. The prevalence of musculoskeletal injuries has increased due to a number of variables, such as decreasing physical activity, higher life expectancy, and professional athleticism. Joint deterioration is a fr [....] » Read More
Title : Biotech scale-up: Bioengineering imperatives in biomanufacturing
Murray Moo Young, University of Waterloo, Canada
During the recent pandemic, it became clear that the main deterrence of manufacturing of newly discovered vaccines was the implementation of prerequisite bioreactor design, operation and control for commercial production. The range of imperatives for success can be wide and compl [....] » Read More
Title : Immunogenicity of therapeutic antibodies: Role of aggregation in T lymphocyte response
Isabelle Turbica, Paris Saclay University, France
Immunogenicity has been described as a major concern to the clinical use of therapeutic antibodies, as treated patients frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response. Among other factors, it is now well a [....] » Read More
Title : Ursodeoxycholic acid is associated with better clinical outcome in COVID - 19 patients: A population based cohort study
Jong Seung Kim, Jeonbuk National University Medical School, Korea, Republic of
Background: Several studies have investigated the relationship between ursodeoxycholic acid (UDCA) and coronavirus disease 2019 (COVID-19). However, complex and conflicting results have caused confusion in the application of these results. We aimed to investigate whether the asso [....] » Read More
Title : The scale-up and culturability of live biotherapeutics for reproductive health in South Africa
Obakeng Jona, University of Cape Town, South Africa
Bacterial vaginosis is a highly prevalent inflammatory condition, characterised by the absence of protective. Lactobacillaceae commensal species and their replacement by vaginal pathogens such as Gardnerella vaginalis. It is known to increase HIV infection rates and thus presents [....] » Read More
Title : Impact of abiotic stress on performance of Nepalese Wheat (Triticum aestivum L.) genotypes and molecular characterization by using stress linked SSR marker
Mukti Ram Poudel, Tribhuwan University, Nepal
Abiotic stresses are the major yield limiting factors for wheat production worldwide. Identification of stable and high yielding genotypes of wheat could be done using additive main effects multiplicative interaction (AMMI) and genotype×genotype×environment biplot (GG [....] » Read More
Title : Improving texture of bacterial cellulose produced by Komagataeibacter xylinus PTCC 1734 by optimization of fermentation parameters
Javad Hamedi, University of Tehran, Iran (Islamic Republic of)
Bacterial cellulose (BC) is a biodegradable and non-toxic polymer that has various applications in various industries, including food industry. Due to having a structure with many pores and a dense network of microfibrils, this biopolymer has a high ability to combine with differ [....] » Read More
Title : Effect of human umbilical cord matrix stem cell conditioned media in cuprizone mice model of multiple sclerosis
Mohsen Marzban, Iranshahr University of Medical Science, Iran (Islamic Republic of)
Introduction: Human Umbilical Cord Matrix Stem Cells (h-UCMSCs) elicit neuroprotective effects, and their repair ability has been investigated in different experimental models. We aimed to investigate the effect of h-UCMSCs supernatant or conditioned media in the cuprizone mice m [....] » Read More
Title : Bioadhesive microneedle patches for tissue sealing
Neta Shimony, Technion, Israel
Sealing of soft tissues prevents leakage of gas and liquid, closes wounds, and promotes healing and is, therefore, of great significance in the clinical and medical fields. Although various formulations have been developed for reliable sealing of soft tissue, tradeoffs between ad [....] » Read More
Title : Indoor biomass fuel as a higher risk factor for TB in HIV positive female patients of Western India
Rajeev Shah, Kiran Medical College, India
Backgroud:-It is well known that one third poor population of world use biomass fuel for cooking and heating. It is universally accepted fact that bio-mass fuel plays a significant role as predisposing factor of tuberculosis, acute respiratory tract infections and COPD even in no [....] » Read More
Title : Genetically modified mosquitoes using CRISPR-Cas9 gene editing technology to inhibit the transmission of the malaria parasite
Miranda Elorm Fiavi, Al Akhawayn University in Ifrane, Morocco
About a quarter billion people are infected with malaria each year, with most cases occurring in sub-Saharan Africa, with a mortality rate of more than 600,000 humans per year. One of the main problems is the superior capacity of the mosquito vectors Anopheles gambiae to acquire [....] » Read More
Title : Invitro regenration of Echinops kebericho from shoot explants
Habtamu, Ethioparents School, Ethiopia
Echinops kebericho is an erect massive rootstock bearing perennial herbs or shrub belonging to the family Asteraceae. Echinops kebericho, endemic to Ethiopia is a critically endangered medicinal plant. It is among few important medicinal plants of the country valued primarily for [....] » Read More
Title : Plant growth promoting characteristics of halo-tolerant endophytic bacteria isolated from Ethiopian rift valley lakes
Solomon Enquahone, Addis Ababa University, Ethiopia
Understanding plant microbes’ intimate relationship and search for beneficial microbes is a sustainable alternative to improve plant growth and yield under a wide range of biotic and abiotic stress conditions. More than 20% of the total global agricultural land is affected [....] » Read More
Title : Effect of eggplant/basil association on the major pests of eggplant under Sudan-Sahelian conditions in Mali
Bibata Ali Outan, National Institute of Agronomic Research of Niger (INRAN), Niger
Eggplant is one of Mali's most widely grown and pest-ridden vegetables. Whitefly (Bemisia tabaci), leafhoppers (Ampoasca spp) and aphids (Aphis gossypii) have a negative impact on production. To minimize the resulting losses, the biological efficacy of basil (Ocimum basilicum [....] » Read More
Title : Morphological, biochemical, and molecular characterization of exotic brassica germplasm
Fawad Ali, Bacha Khan University Charsadda, Pakistan
Oilseed rape (Brassica napus L.) is an important oilseed crop. We examined the diversity of germplasm expressed at three distinct levels (i.e., morphological, biochemical, and DNA levels). For this study, the Bio resources Conservation Institute provided 150 B. napus L. accession [....] » Read More
Title : Molecular epidemiology of Hepatitis B virus (HBV) genotypes prevalent in KP
Farzana Na, Women University Mardan, Pakistan
Hepatitis B virus (HBV) infection is a major public health dilemma affecting about 2 billion of world population and more than 350 million people are chronically HBV carriers including Pakistan with an estimated prevalence rate of 3%. HBV can be categorized into 10 genotypes (A-H [....] » Read More
Title : Valorization of wastes via a one-step microbial fermentation process
Fernando Santos Beneit, University of Valladolid, Spain
Pollution from plastic waste represents one of the most relevant environmental problems that our society currently faces. Most conventional plastics are extremely recalcitrant, with estimated decomposition times of decades to centuries. However, the production of plastics increas [....] » Read More
Title : The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction
Youngwook Ham, Korea Research Insitute of Bioscience and Biotechnology, Korea, Republic of
The COVID-19 pandemic is an ongoing global public health threat. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and binding of the SARS-CoV-2 spike to its receptor, angiotensin-converting enzyme 2 (ACE2), on host cells is critical fo [....] » Read More
Title : Production of hydroxyectoine with an engineered strain of Methylomicrobium alcaliphilum
Sergio Bordel, University of Valladolid, Spain
Methylomicrobium alcaliphilum is a halotolerant methanotroph, which produces ectoine under high salinity conditions. Ectoine is an osmoprotector and protein stabilizer that allows microorganisms to survive at high salt concentrations (up to 9% in the case of M. alcaliphilum) and [....] » Read More
Title : Water biosense?, An innovative technology for real-time monitoring of biological agents and biomarkers of health and environmental interest in water
Ivan Iglesias Baena, Sensactive Technology S.L., Spain
Drought is an increasingly frequent phenomenon with significant impacts on the economy, quality of life, and the environment. According to the World Health Organization, more than 2 billion people suffer water scarcity, a situation exacerbated by climate change and population gro [....] » Read More
Title : Nano gold-enhanced bioglass: Unveiling in vitro and in vivo bioactivity characteristics for advanced medical applications
Yousef Alobaisi, King Fahad Medical City, Saudi Arabia
Incorporated gold ions Au into glass with composition 30P2O5-20Ca(OH)2-20ZnO8.0KF-5B2O3-2.0TiO2 in mol% with 400ppm (Gold III Chloride trihydrate HAuCl4-3H2O) and 600ppm (Gold III Chloride trihydrate HAuCl4-3H2O) by using terdiurnal method quenching method. The present glass' [....] » Read More
Title : Fabrication of symbiotic multicellular assemblies by using a novel “Gel Layer-by-Gel Layer” technique
Reem Alhaidose, Ministry Of Municipality - Biotech Center, Qatar
The research on biofilms has skyrocketed in recent years due to increased awareness of the pervasiveness and impact of biofilms on natural and industrial systems, as well as human health. A biofilm is a well-organized, cooperating community of microorganisms. Microbial cells atta [....] » Read More
Title : Cloning and characterization of a vasa homolog in the giant grouper (Epinephelus lanceolatus) and its specifically expression in gonad
Surintorn Boonanuntanasarn, Suranaree University of Technology, Thailand
The vasa gene has been the most used as a gene marker for germ cell in vertebrate; particularly in fish. This study cloned and characterized a vasa homolog in the giant grouper (Epinephelus lanceolatus) and designated as Elvasa. Our result showed that Elvasa contained predicted r [....] » Read More
Title : Expression of Tc-MypPA gene involved in the regulation of the biosynthesis of proanthocyanidins in some cocoa beans (Theobroma cacao L.)
Manga Ndjaga Jude, University of Yaounde I, Cameroon
Proanthocyanidins (PAs) are known as flavor precursors of a chocolate. In the course postharvest processes (fermentation and drying), PAs impart astringency and bitterness to many cocoa bean genotypes. The goal of this work was therefore to see if there was a relationship between [....] » Read More