Sebastian Oltean, University of Exeter Medical School, United Kingdom
Alternative splicing is known to occur in more than 94% if genes in humans. Cancers express specific splice isoforms, or the normal ratios of isoforms are disrupted. While some of these events may be just a silent by-product of the cancer progression, many of them have functional [....] » Read More
Title : Pressure plate analysis in musculoskeletal injuries: An overview
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal injuries are extremely common in both humans and Animals. The prevalence of musculoskeletal injuries has increased due to a number of variables, such as decreasing physical activity, higher life expectancy, and professional athleticism. Joint deterioration is a fr [....] » Read More
Title : Biotech scale-up: Bioengineering imperatives in biomanufacturing
Murray Moo Young, University of Waterloo, Canada
During the recent pandemic, it became clear that the main deterrence of manufacturing of newly discovered vaccines was the implementation of prerequisite bioreactor design, operation and control for commercial production. The range of imperatives for success can be wide and compl [....] » Read More
Title : Immunogenicity of therapeutic antibodies: Role of aggregation in T lymphocyte response
Isabelle Turbica, Paris Saclay University, France
Immunogenicity has been described as a major concern to the clinical use of therapeutic antibodies, as treated patients frequently develop anti-drug antibodies (ADA) with potential neutralizing capacities leading to loss of clinical response. Among other factors, it is now well a [....] » Read More
Title : Ursodeoxycholic acid is associated with better clinical outcome in COVID - 19 patients: A population based cohort study
Jong Seung Kim, Jeonbuk National University Medical School, Korea, Republic of
Background: Several studies have investigated the relationship between ursodeoxycholic acid (UDCA) and coronavirus disease 2019 (COVID-19). However, complex and conflicting results have caused confusion in the application of these results. We aimed to investigate whether the asso [....] » Read More
Title : The scale-up and culturability of live biotherapeutics for reproductive health in South Africa
Obakeng Jona, University of Cape Town, South Africa
Bacterial vaginosis is a highly prevalent inflammatory condition, characterised by the absence of protective. Lactobacillaceae commensal species and their replacement by vaginal pathogens such as Gardnerella vaginalis. It is known to increase HIV infection rates and thus presents [....] » Read More
Title : Impact of abiotic stress on performance of Nepalese Wheat (Triticum aestivum L.) genotypes and molecular characterization by using stress linked SSR marker
Mukti Ram Poudel, Tribhuwan University, Nepal
Abiotic stresses are the major yield limiting factors for wheat production worldwide. Identification of stable and high yielding genotypes of wheat could be done using additive main effects multiplicative interaction (AMMI) and genotype×genotype×environment biplot (GG [....] » Read More
Title : Improving texture of bacterial cellulose produced by Komagataeibacter xylinus PTCC 1734 by optimization of fermentation parameters
Javad Hamedi, University of Tehran, Iran (Islamic Republic of)
Bacterial cellulose (BC) is a biodegradable and non-toxic polymer that has various applications in various industries, including food industry. Due to having a structure with many pores and a dense network of microfibrils, this biopolymer has a high ability to combine with differ [....] » Read More
Title : Effect of human umbilical cord matrix stem cell conditioned media in cuprizone mice model of multiple sclerosis
Mohsen Marzban, Iranshahr University of Medical Science, Iran (Islamic Republic of)
Introduction: Human Umbilical Cord Matrix Stem Cells (h-UCMSCs) elicit neuroprotective effects, and their repair ability has been investigated in different experimental models. We aimed to investigate the effect of h-UCMSCs supernatant or conditioned media in the cuprizone mice m [....] » Read More
Title : Bioadhesive microneedle patches for tissue sealing
Neta Shimony, Technion, Israel
Sealing of soft tissues prevents leakage of gas and liquid, closes wounds, and promotes healing and is, therefore, of great significance in the clinical and medical fields. Although various formulations have been developed for reliable sealing of soft tissue, tradeoffs between ad [....] » Read More
Title : Indoor biomass fuel as a higher risk factor for TB in HIV positive female patients of Western India
Rajeev Shah, Kiran Medical College, India
Backgroud:-It is well known that one third poor population of world use biomass fuel for cooking and heating. It is universally accepted fact that bio-mass fuel plays a significant role as predisposing factor of tuberculosis, acute respiratory tract infections and COPD even in no [....] » Read More
Title : Genetically modified mosquitoes using CRISPR-Cas9 gene editing technology to inhibit the transmission of the malaria parasite
Miranda Elorm Fiavi, Al Akhawayn University in Ifrane, Morocco
About a quarter billion people are infected with malaria each year, with most cases occurring in sub-Saharan Africa, with a mortality rate of more than 600,000 humans per year. One of the main problems is the superior capacity of the mosquito vectors Anopheles gambiae to acquire [....] » Read More
Title : Invitro regenration of Echinops kebericho from shoot explants
Habtamu, Ethioparents School, Ethiopia
Echinops kebericho is an erect massive rootstock bearing perennial herbs or shrub belonging to the family Asteraceae. Echinops kebericho, endemic to Ethiopia is a critically endangered medicinal plant. It is among few important medicinal plants of the country valued primarily for [....] » Read More
Title : Plant growth promoting characteristics of halo-tolerant endophytic bacteria isolated from Ethiopian rift valley lakes
Solomon Enquahone, Addis Ababa University, Ethiopia
Understanding plant microbes’ intimate relationship and search for beneficial microbes is a sustainable alternative to improve plant growth and yield under a wide range of biotic and abiotic stress conditions. More than 20% of the total global agricultural land is affected [....] » Read More
Title : Effect of eggplant/basil association on the major pests of eggplant under Sudan-Sahelian conditions in Mali
Bibata Ali Outan, National Institute of Agronomic Research of Niger (INRAN), Niger
Eggplant is one of Mali's most widely grown and pest-ridden vegetables. Whitefly (Bemisia tabaci), leafhoppers (Ampoasca spp) and aphids (Aphis gossypii) have a negative impact on production. To minimize the resulting losses, the biological efficacy of basil (Ocimum basilicum [....] » Read More
Title : Morphological, biochemical, and molecular characterization of exotic brassica germplasm
Fawad Ali, Bacha Khan University Charsadda, Pakistan
Oilseed rape (Brassica napus L.) is an important oilseed crop. We examined the diversity of germplasm expressed at three distinct levels (i.e., morphological, biochemical, and DNA levels). For this study, the Bio resources Conservation Institute provided 150 B. napus L. accession [....] » Read More
Title : Molecular epidemiology of Hepatitis B virus (HBV) genotypes prevalent in KP
Farzana Na, Women University Mardan, Pakistan
Hepatitis B virus (HBV) infection is a major public health dilemma affecting about 2 billion of world population and more than 350 million people are chronically HBV carriers including Pakistan with an estimated prevalence rate of 3%. HBV can be categorized into 10 genotypes (A-H [....] » Read More
Title : Valorization of wastes via a one-step microbial fermentation process
Fernando Santos Beneit, University of Valladolid, Spain
Pollution from plastic waste represents one of the most relevant environmental problems that our society currently faces. Most conventional plastics are extremely recalcitrant, with estimated decomposition times of decades to centuries. However, the production of plastics increas [....] » Read More
Title : The SpACE-CCM: A facile and versatile cell culture medium-based biosensor for detection of SARS-CoV-2 spike-ACE2 interaction
Youngwook Ham, Korea Research Insitute of Bioscience and Biotechnology, Korea, Republic of
The COVID-19 pandemic is an ongoing global public health threat. COVID-19 is caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection, and binding of the SARS-CoV-2 spike to its receptor, angiotensin-converting enzyme 2 (ACE2), on host cells is critical fo [....] » Read More
Title : Production of hydroxyectoine with an engineered strain of Methylomicrobium alcaliphilum
Sergio Bordel, University of Valladolid, Spain
Methylomicrobium alcaliphilum is a halotolerant methanotroph, which produces ectoine under high salinity conditions. Ectoine is an osmoprotector and protein stabilizer that allows microorganisms to survive at high salt concentrations (up to 9% in the case of M. alcaliphilum) and [....] » Read More
Title : Water biosense?, An innovative technology for real-time monitoring of biological agents and biomarkers of health and environmental interest in water
Ivan Iglesias Baena, Sensactive Technology S.L., Spain
Drought is an increasingly frequent phenomenon with significant impacts on the economy, quality of life, and the environment. According to the World Health Organization, more than 2 billion people suffer water scarcity, a situation exacerbated by climate change and population gro [....] » Read More
Title : Nano gold-enhanced bioglass: Unveiling in vitro and in vivo bioactivity characteristics for advanced medical applications
Yousef Alobaisi, King Fahad Medical City, Saudi Arabia
Incorporated gold ions Au into glass with composition 30P2O5-20Ca(OH)2-20ZnO8.0KF-5B2O3-2.0TiO2 in mol% with 400ppm (Gold III Chloride trihydrate HAuCl4-3H2O) and 600ppm (Gold III Chloride trihydrate HAuCl4-3H2O) by using terdiurnal method quenching method. The present glass' [....] » Read More
Title : Fabrication of symbiotic multicellular assemblies by using a novel “Gel Layer-by-Gel Layer” technique
Reem Alhaidose, Ministry Of Municipality - Biotech Center, Qatar
The research on biofilms has skyrocketed in recent years due to increased awareness of the pervasiveness and impact of biofilms on natural and industrial systems, as well as human health. A biofilm is a well-organized, cooperating community of microorganisms. Microbial cells atta [....] » Read More
Title : Cloning and characterization of a vasa homolog in the giant grouper (Epinephelus lanceolatus) and its specifically expression in gonad
Surintorn Boonanuntanasarn, Suranaree University of Technology, Thailand
The vasa gene has been the most used as a gene marker for germ cell in vertebrate; particularly in fish. This study cloned and characterized a vasa homolog in the giant grouper (Epinephelus lanceolatus) and designated as Elvasa. Our result showed that Elvasa contained predicted r [....] » Read More
Title : Expression of Tc-MypPA gene involved in the regulation of the biosynthesis of proanthocyanidins in some cocoa beans (Theobroma cacao L.)
Manga Ndjaga Jude, University of Yaounde I, Cameroon
Proanthocyanidins (PAs) are known as flavor precursors of a chocolate. In the course postharvest processes (fermentation and drying), PAs impart astringency and bitterness to many cocoa bean genotypes. The goal of this work was therefore to see if there was a relationship between [....] » Read More