L-asparaginase is an antileukemic enzyme that is majorly utilized in the treatment of acute lymphoblastic leukaemia (ALL) and other blood cancers. A number of groups have made efforts to explore this vital agent. However, the use of L-asparaginase has been observed to have severa [....] » Read More
The healthcare and pharmaceutical industries need ever more performing, safe and economical solutions for both diagnostic and therapeutic applications including anti-inflammatory, antioxidant and antitumor remedies, but also nutraceutical and cosmeceutical preparations. Since man [....] » Read More
Nanotechnology is used in the discovery and production of the novel physicochemical features of nanoscale materials used in industry and medicine. Applications of nanotechnology are used by infectious disease professionals and public health researchers to identify, treat, and pre [....] » Read More
The problem of antibiotic resistance is becoming more and more serious, one of the causes is due to the mechanism of biofilm formation that prevents antibiotics from contacting bacteria, and at the same time spreading antibiotic resistance genes in the bacterial population. Scaph [....] » Read More
Plant tissues are natural sources of bioactive molecules to control pathogens that cause infections, as they contain secondary metabolites with antimicrobial activities. Terpenoids especially have been the subject of a considerable number of investigations that uncovered extensiv [....] » Read More
RNA interference is a post-transcriptional modification of gene silencing mechanism. It presents in a wide range of organisms like plants, fungi, both vertebrates and invertebrates and inside of the most important mammals. As short RNAi mechanism can apply by double-stranded shor [....] » Read More
Artemisinin is an effective antimalarial sesquiterpene lactone synthesized in Artemisia annua. Artemisinin-based combination therapies (ACTs) are recommended by the World Health Organization (WHO) as the best choice to cure acute malaria. Many transcription factors regulating art [....] » Read More
Nanofiltration, a relatively new synthetic membrane-based separation process was first used to fractionate lignocellulosic hydrolysate. The fractionated streams of permeate and retentate were fermented separately to produce bioethanol in high yield. The choice of the right nanofi [....] » Read More
As antibiotics are widely used in medical and agricultural applications, the development of antibiotic resistance (AMR) continues to diversify and raise serious public concerns. Although AMR naturally occurs, the lack of antibiotic use in recent decades has contributed to its rap [....] » Read More
Escherichia coli, Salmonella enterica, Acinetobacter baumannii, Pseudomonas aeguginosa, Enterococcus faecium and Klebsilla pneumoniae etc mediated infections were not cured by conventional antibiotics due to presence of multiple large and small MDR plasmids with >10 mdr (amp, [....] » Read More
The Great Indian Desert, also known as the Thar Desert, covers approximately 0.32 million km2 of the planet's surface, or 10% of India's whole geographic area. Despite being one of the smallest deserts in the world, it is home to a variety of habitats and species. One of [....] » Read More
Neurodegenerative Diseases affect millions of people worldwide. Neurodegenerative diseases develop when neuron cells within the brain or peripheral nervous system gradually lose their ability to function and eventually die. The condition has no cure, even though therapies may hel [....] » Read More
The side effects of existing drugs and other methods, which are effective in decreasing the progression of cancer, are quite harmful and toxic to our bodies. To tackle this, a safer method needs to be derived. Dietary and their gut metabolized chemicals are being explored for inh [....] » Read More
Chronic Obstructive Pulmonary Disease (COPD) and Lung cancer are the major reasons for lung disease related mortality worldwide. Chronic inflammation is a key attribute of COPD and a potential driver of lung carcinogenesis. Among various environmental risk factors, cigarette smok [....] » Read More
Nitric Oxide (NO), a signal molecule plays vital role to provide tolerance to abiotic stress in plants by interplay with reactive oxygen species, and thus promoting their growth and development. Arsenic (As) is a toxic metalloid and its contamination found in crop plants, mainly [....] » Read More
Background: Plant-specific transcription factors (TFs) named SQUAMOSA promoter binding protein-like (SPL) proteins have a number of developmental roles in plants, including growth, flowering, and signal transduction. A gene family that encodes SPL proteins has been identified in [....] » Read More
RNA Recognition Motifs (RRMs) being the most abundant RNA binding domain in eukaryotes, is a major player in cellular regulation. Human DND1 (dead-end protein homolog1) also known as microRNA-mediated repression inhibitor 1 is an RNA-binding protein containing two RRMs in ta [....] » Read More
Carboxylesterases (CEs) are hydrolytic enzymes involved in anticancer drug metabolism. Human WHO grades all meningiomas and gliomas exhibited lower CE-specific activity which proves one of the main reasons for the failure of chemotherapy. The similar CE-specific activity bet [....] » Read More
A prolonged battle to win over mutational hazards still remains unconquered by mankind. At present, major thrust area of research is aimed at giving a maximum benefit to human civilization. In the present context of globalization, biotechnology will dominate the scenario. Allopat [....] » Read More
Photocatalysts have been studied for a variety of applications in biotechnology, including in the field of medicine, agriculture, and environmental biotechnology. In medicine, photocatalysts have been studied for their ability to kill bacteria and viruses, and have been used in t [....] » Read More
According to UNAIDS, there were approximately 37.9 million people across the globe with HIV/AIDS in 2018. Of these, 36.2 million were adults and 1.7 million were children (< 15 years old). New HIV infection – An estimated 1.7 million individuals worldwide were newly infe [....] » Read More
Agricultural production of arable crops will necessarily call on the full range of available solutions: choice and rotation of crops, tillage, fertilizers, phytosanitary products, biological control of pests, varietal selection, irrigation...etc. Today, the arable crops sector us [....] » Read More
The Study was conducted at Riyadh, Saudi Arabia to Isolate and Identify the Azospirillium zeae from Acacia tortilis. Useful bacteria associated with the plant roots have the potential to alleviate the burden of using costly and harmful agrochemicals in harsh environments. Finding [....] » Read More
Intellectual disability is characterized by a significant impaired intellectual and adaptive functioning, affecting approximately 1 to 3% of the population, which can be caused by a variety of environmental and genetic factors. In this respect, de novo heterozygous HECW [....] » Read More
Bacterial canker caused by the bacterium Clavibacter michiganensis subsp. michiganensis (Cmm) is one of the most feared diseases of solanaceous crops in the greenhouse as well as in the field, especially tomato and bell pepper. In Morocco, Agadir, is well known for intensive prod [....] » Read More
Context: Coronary artery disease (CAD) is one of the common diseases in patients with type two diabetes mellitus (T2DM). The nuclear hormone receptor peroxisome proliferator-activated receptor-gamma (PPARγ) plays a vital role in dyslipidemia, and oxidative stress is in [....] » Read More
The microbial electrolysis cell (MEC) is an emerging technology for bioenergy production using organic wastewater. Normally, a pre assimilated bio-anode is utilized by the MEC to break down the organic content, but the formation and assimilation of microbial community at the anod [....] » Read More
Pesticides are broadly used to protect crops from harmful insects, weeds, and other bio-forms that cause plant diseases. Agriculture workers in Pakistan are continuously exposed to different pesticides including Pyrethroid (PYR) and Organophosphate (OPs). To determine the cytotox [....] » Read More
Yeasts are the second major cause of infections that occur in the human body. Certain conditions viz., diabetes, HIV, GIT surgery, corticosteroid usage, organ transplant and cancer increase the risk to develop an oral yeast infection. A current study was carried out on the preval [....] » Read More
The expression of a set of genes in a metabolic pathway can be regulated by a single transcription factor (TF). The use of TFs can, therefore, be a promising strategy for generating plants with superior traits. Triticum aestivum Dof1 TF is known to regulate nitrogen assimilation [....] » Read More
Resistant thermophilic strain was isolated from wastewater and recognized as Anoxybacillus rupiensis on the basis of 16S rRNA gene sequence analysis. It was grown in LB media at 60oC with pH 7.0. It showed typical growth pattern except for the lag phase extended in the presence o [....] » Read More
Pakistan is an agricultural country. Abiotic and biotic stresses lead to the poor germination of plants by spreading hindrance in the natural mechanism of plant growth and development. Among crop growth promoting rhizobacteria, gram negative Azotobacter proves to be a powerful ca [....] » Read More
The field of molecular biology has brought many innovations in biodiversity research, with the emerging field of DNA barcoding, which is having a growing impact on plant identification. In DNA barcoding, standard molecular markers are used for species identification of the materi [....] » Read More
Lactic acid bacteria (LAB) can be defined as gram-positive, acid-tolerant, generally non-sporulating, non-respiring, either rod-shaped (bacilli) or spherical (cocci) bacteria that share common metabolic and physiological characteristics. These bacteria are usually found in decomp [....] » Read More
Title : Biosurfactants: Production and novel applications
Cristiano Jose de Andrade, Federal University of Santa Catarian (UFSC), Brazil
Biosurfactants are amphipathic molecules that can be applied in a wide range of areas. These compounds can be widely used in industries as pharmaceutical agents, and for microbial-enhanced oil recovery, among others. Amongst these biosurfactants, surfactin, rhamnolipids, and mann [....] » Read More
Title : Tailoring composition, bioactivity, and porous structure of 3D-printed scaffolds for tissue engineering
Dario Puppi, University of Pisa, Italy
Will be Updated Soon...
Title : From mesenchymal stromal/Stem cells to insulin-producing cells: Progress and challenges
Mohamed A Ghoneim, Urology and Nephrology Center, Egypt
Mesenchymal stromal cells (MSCs) provide an attractive option for cell therapy for type 1 diabetes mellitus (DM). These cells have multiple sources, but bone marrow and adipose tissue are the most studied. Allogenic adipose tissue-derived MSCs (ATMSCs) are widely available as a b [....] » Read More
Title : A Review of Nanomaterials in Humans
Thomas J Webster , Hebei University of Technology, United States
Nanotechnology is now a mature field in numerous industries from energy to building constructs to medicine. Nanomaterials have specifically revolutionized how we prevent, diagnose, and treat diseases. In this presentation, a review of the use of nanomaterials in humans will be pr [....] » Read More
Title : Analyzing functioning and quality of life with 3D printed prosthetic hands
Regina Rossi, Alvernia University, United States
Around the world, there are 40 million people with amputations, and more than 1 million people lose a limb each year (Donnelley et al., 2021; Marino et al., 2015). According to the World Health Organization, when individuals can obtain prosthetics, they are able to live more prod [....] » Read More
Title : Influence of proteins extracted from tarantula spider silk on the survival of mesenchymal stem cells
Dauddin Daudi, ITMO, Russian Federation
The skin is the largest organ in the human body. The skin's main function is barrier, and it protects internal organs, so it accounts for the greatest amount of damage. Wound healing is a complex process involving the interaction of cells and matrixes with further formation o [....] » Read More
Title : Microbes-enabled sustainable biomanufacturing of food, chemical and medicine
Congqiang Zhang, Agency for Science, Technology and Research, Singapore
In the natural food chain, plants/algae are the producers, animals are the consumer and microbes are the decomposer. A recent technological breakthrough in synthetic biology has broadened the role of microbes. Microbial cells have now become a great “producer” or &ldq [....] » Read More
Title : Using computational synthetic biology tools to modulate gene expression within a microbiome
Liyam Chitayat Levi, Tel Aviv University, Israel
The microbiome is an interconnected network of microorganisms, which exist and influence a wide array of natural and synthetic environments. Genetic information is constantly spread across the members of the microbial community, in a process called horizontal gene transfer, causi [....] » Read More
Title : Bio-valorization of bioemulsifiers/biosurfactants produced by lactobacilli isolated from an indigenous fermented milk (Pendidam) of the Adamaoua region of Cameroon : A bio-therapeutic perspective to fight against aids, COVID-19, influenza, hepatitis b and c, myocardial infarction and cerebro-vascular accident
Mbawala Augustin, University of Ngaoundere, Cameroon
Nowadays, the number of outbreaks of epidemics associated with viral infection and mortality due to myocardial infarction (MI) and cerebrovascular accident (CVA) has increased significantly. The recent emergence of several strains of Influenza viruses with pandemic potentials as [....] » Read More
Title : Biomonitoring of human enteropathogenic microsporidian spores in groundwater of two sub-divisions in the centre region (cameroon) : Impact of physico-chemical factors
Asi Quiggle Atud, University of Yaounde I, Cameroon
Microsporidia is an emerging opportunistic disease, dangerous, and very resistant to water. They are poorly known in Sub-Saharan Africa with high prevalence in the immunocompromised patient (Acquired Immunodeficiency Syndrome patient). In sub-urban and rural areas population arou [....] » Read More
Title : Antibiotic-resistant strains of Klebsiella pneumoniae harbouring novel virulence proteins with rising temperature
Mohammad AL Mamun, University of Science and Technology Chittagong, Bangladesh
Antimicrobial resistance (among bacteria and other germs) is a significant cause of concern because it is reported/expected to result in as many as 10 million deaths worldwide by 2050 (1-3). Overuse of antibiotics, a slow discovery of new antibiotics, a shortage of healthcare res [....] » Read More
Title : Anti-sickling activity of aqueous extracts from the bark of daniellia oliveri (Rolfe) Hutch. & dalziel. In the management of sickle cell disease in Benin
Senou Maximin, National University of Sciences, Technologies, Engineering and Mathematics (UNSTIM), Benin
Context : Daniellia oliveri was a plant used in Benin in the treatment of sickle cell crises. It was one of the many traditional plants whose virtues have not yet been scientifically proven. Objective : To evaluate the effectiveness of the aqueous extract of the bark of Daniel [....] » Read More
Title : Performance and stability of nepalese wheat genotypes under irrigated, drought and heat stress environments and genetic diversity of wheat genotypes by using stress tolerance linked marker
Mukti Ram poudel, Tribhuwan University, Nepal
Wheat is a major cereal crop important for human nutrition and plays a vital role in food security of Nepal. Present study aimed at identifying high yielding, drought and heat adapted wheat lines and understanding the variation of yield attributing characters under the rising tem [....] » Read More
Title : Surface evaluation of curing potentials of homodium bromide, acridine orange, thioridaxine, elevated temperature, ascorbic acid and plant products (Garlic, Apple cider vinegar) on selected multidrug resistant bacterial pathogens
Festus Dafinone Otajevwo, Western Delta University, Nigeria
Microbial infections are presently posing major health threats worldwide and this may be because a number of infections such as urinary tract infections, pneumonia, tuberculosis, gonorrhea, meningitis, pharyngitis, salmonellosis etc are becoming more difficult to treat largely ow [....] » Read More
Title : Assessment of faecal carriage of ampc producing e. Coli and klebsiella spp among some students
Iyevhobu Kenneth Oshiokhayamhe, National Open University of Nigeria, Nigeria
AmpC-producing organisms can act as a hidden reservoir for ESBLs; the high-level expression of the AmpC β-lactamases may mask the recognition of the ESBLs. In recent years, the world has seen a surge in Enterobacteriaceae resistant to broad-spectrum betalactam antibiotics du [....] » Read More
Title : Characterization of microorganisms associated with post harvest decay of some varieties of mango (Mangifera indica Linn) Grown in Benue state, Nigeria
Ejeikwu Emmanuel oloja, University of abuja, Nigeria
The microorganisms associated with the decay of the fruits of some varieties of Mango [Mangifera indica Linn] in Benue State, Nigeria have been examined using standard protocols. The Mango varieties studied were Broken, Goat Head, Julie, Parrot Mouth, Peter and Sweet Mango. Fresh [....] » Read More
Title : Biotechnology in faidherbia albida in the Sudano sahelian zone of Cameroon
Tchatchoua Dorothy Tchapda, University of Maroua, Cameroon
Cameroon is the only Africa country which is described as African in Miniature. It is in the Central African region and bordered by Nigeria, Chad, Central Africa Republic Equatorial Guinea, Gabon, and the Republic of Congo. Cameroon is divided into ten regions with different agro [....] » Read More
Title : Comparison of different nanofiber scaffolds effects on bone regeneration of calvaria defect in a Wistar rat model - Importance of porosity
Fanny Gimie, Gip cyroi, France
Skeletal tissue injury is a major burden on the global healthcare system due to an aging population. In addition, metabolic disorders such as diabetes and osteoporosis further impede the healing process. Tissue engineering scaffold for reconstructive strategies offer exciting opp [....] » Read More
Title : Protective effect of ginkgo biloba extract against diclofenac induced nephrotoxicity
Sally mahmoud ibrahim, Mansoura university, Egypt
The objective of the present study was to evaluate the ability to orally administration of Ginkgo biloba (G.b) extract against kidney damage induced by diclofenac (DF) in male rats with different doses and times The experimental rats were divided into six groups that further divi [....] » Read More
Title : Sequencing analysis of pyelonephritis-associated pili Gene of uro-pathogenic escherichia coli isolated from iraqi patients from Baghdad
Maysaa Abdul razzaq dhahi, Al Nahrain University, Iraq
Pyelonephritis-associated pili (Pap) fimbria considered as the main adhesive virulence factor that enable Escherichia coli(E. coli) to colonize in the urinary tract and resist the avoiding by the flow of urine. DNA adenine methyl-transferase gene (Dam) have a role in regulation o [....] » Read More
Title : Exosome-based strategies for diagnosis and therapy of glioma cancer
Alireza masoudi, Medical university of Qom, Iran (Islamic Republic of)
Glioblastoma belongs to the most aggressive type of cancer with a low survival rate that is characterized by the ability in forming a highly immunosuppressive tumor microenvironment. Intercellular communication are created via exosomes in the tumor microenvironment through the tr [....] » Read More