TNAs, or therapeutic nucleic acids, are nucleic acids or closely related compounds that are used to cure disease. TNAs come in a variety of shapes and sizes, but they all have the same mode of action: sequence specific recognition of endogenous nucleic acids via Watson–Crick base pairing. The growing number of FDA-approved nucleic acid therapies shows that diseases can be treated in vivo by addressing their genetic blueprints. Because they target proteins rather than the underlying reasons, traditional therapies typically have transitory therapeutic results. Nucleic acid treatments, on the other hand, can achieve long-lasting or even curative effects by inhibiting, replacing, or altering genes. However, delivery strategies that improve stability, enable internalisation, and boost target affinity are required for clinical translation. Synthetic biology, systems biology, computational biology, bioinformatics, and nanotechnology, among other fields, have accelerated progress and established a new paradigm for nucleic acids in therapy.
Title : Biosurfactants: Production and novel applications
Cristiano Jose de Andrade, Federal University of Santa Catarian (UFSC), Brazil
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Dario Puppi, University of Pisa, Italy
Title : From Mesenchymal Stromal/Stem Cells to Insulin-Producing Cells: Progress and Challenges
Mohamed A Ghoneim, Urology and Nephrology Center, Egypt
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Ta Ngoc Ly, Danang University of Technology and Science, Vietnam
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Regina Rossi, Alvernia University, United States
Title : Nanofiltration Mediation for Efficient Production of Second Generation Bioethanol by Wild-Type Yeast from Lignocellulosic Hydrolysate
Gopal Prasad Agarwal, Indian Institute of Technology Delhi, India