I will review the tangible improvements my colleagues and I have achieved in novel biomarkers across various clinical specialties, and which have led to more accessible, affordable, and accurate diagnostics. Partially, these advances are due to non-trivial computational analyses [....] » Read More
Weeds outcompete crops for natural resources, reducing productivity (growth, yields) and quality of products. Globally, the annual worth of agrochemicals used to protect crops from weeds is estimated to US$75.3 billion. Blind use of chemicals to maximize production ensuring food [....] » Read More
This talk highlights innovative strategies for utilizing microbial systems to produce biofuels, biochemicals, and high-value biomolecules from lignocellulosic biomass and other renewable resources. Key focus areas include microbial fermentation, bioreactor design, enzymatic and b [....] » Read More
Extracellular Vesicles (EVs) are lipid bilayer–enclosed nanoparticles released by virtually all cells and are now recognized as key mediators of intercellular communication. Their capacity to transfer lipids, proteins, nucleic acids, and metabolites has spurred intense inte [....] » Read More
Group B Streptococcus (GBS) is a leading cause of neonatal infection, meningitis, and pneumonia, yet existing diagnostic methods are time-consuming or dependent on specialised laboratories, limiting their use for early screening during pregnancy. To address this challenge, we use [....] » Read More
Despite advancements in agriculture and farming over the years, hunger (defined as “an uncomfortable or painful physical sensation caused by insufficient consumption of dietary energy”) continues to increase in some parts of the world. The author of this work argues t [....] » Read More
Environmental biotechnology (EB) implies application of biological systems to solve ecological problems, manage waste, and reduce pollution. Biological systems refer to microorganisms, plants, and enzymes. EB touches upon biochemistry, microbiology, and environmental engineering [....] » Read More
Antimicrobial resistance (AMR) is no longer a looming threat - it is an active crisis. The World Health Organization estimates that drug-resistant infections already claim over 1.27 million lives annually, with projections suggesting the toll could reach 10 million per year [....] » Read More
Non-small cell lung cancer (NSCLC) remains difficult to treat because nearly half of cases lack targetable mutations and often develop therapy resistance, making epigenetic reprogramming an attractive therapeutic strategy. The current study investigates how Signal Transducer and [....] » Read More
Despite unprecedented advances in molecular biology, genomics, biomarker discovery, artificial intelligence and translational science, the probability that a drug entering clinical development will ultimately reach patients remains remarkably low. Why do apparently promising mole [....] » Read More
Implant infection is rising with the U.S. Centers for Disease Control predicting one person every three seconds will die from a bacteria infection by 2050. Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundr [....] » Read More
Silk fibroin (SF) and chitosan (CS) are biopolymers widely studied as resorbable scaffolds for regenerative medicine. In this study, SF/CS composite plugs were prepared at 70:30 and 60:40 ratios and compared with single-polymer controls to evaluate their physicochemical propertie [....] » Read More
Health systems and health trends are always changing. Since no health system is flawless, a complement is required. As a result, practitioners of Western medicine (WM) are searching for traditional medicine Ayurveda (TM), and vice versa, since TM is better at treating chron [....] » Read More
Antimicrobial resistance (AMR) has evolved as major public health challenges worldwide. Disease causing microorganism become resistant day by day due to various factors. The speedy evolution of multidrug-resistant disease causing microorganisms necessitates the development of inn [....] » Read More
Cancer is a major reason of death worldwide in human beings and traditional chemotherapy is usually connected with poor specificity, systemic toxicity and unwanted side effects. Nanoparticles based targeted drug delivery systems have come out as a favourable approach to overcome [....] » Read More
The concept of biostimulants has become firmly established worldwide as a key strategy in modern, sustainable agriculture, aimed at enhancing crop yield and resilience. These tools act as a complement that potentiates natural physiological processes, improving nutrient-use effici [....] » Read More
Biological systems can undergo transitions between alternative organizational states, including cellular differentiation, developmental reorganization, multicellular organization, and other forms of biological restructuring. A central question is whether the degree of regulatory [....] » Read More
Pomegranate fruit is recognized for its potential benefits to oxidative and vascular health, effects that have been partly attributed to its ellagitannin constituents. However, whether pomegranate ellagitannins can attenuate the adverse metabolic effects associated with excessive [....] » Read More
Title : Steps and strides: Cross-species insights into movement and injury
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal disorders are a major cause of pain, functional limitation, and reduced quality of life, with increasing prevalence driven by aging, obesity, and physical inactivity. Early and accurate diagnosis remains a persistent clinical challenge, particularly when assessmen [....] » Read More
Title : Genetic engineering for the reduction of high mannose species in biopharmaceutical-producing CHO cells
Melissa Morra, University of Turin/Merck KGaA, Italy
In biopharmaceutical manufacturing, approximately 60-70% of all recombinant proteins are produced in mammalian cells, with Chinese Hamster Ovary (CHO) cells representing the preferred expression system. Clinical efficacy and safety can be significantly affected by the glycosylati [....] » Read More
Title : Process intensification for the continuous production of alternative proteins
Laura Pasitka, GEA Liquid Technologies Germany GmbH, Germany
Optimizing equipment utilization in biotechnological manufacturing systems remains a central challenge during the scale-up transition from laboratory to industrial production. Substantial research and development focus on process intensification and transforming batch and fed-bat [....] » Read More
Title : Process parameter optimization for enhancing pigment productivity in chlorella vulgaris
Akanksha Singh, Indian Institute of Technology Kharagpur, India
Microalgae are recognized as promising biofactories for producing a range of industrially valuable and economically significant products. Microalgal cultivation for high-value pigments often suffers from economic bottlenecks due to low productivity under standard conditions. This [....] » Read More
Title : Redefining oral cancer detection: The role of AI-based biotechnological methods beyond conventional technologies—a systematic review
Surbhi Priyadarshi, SGT University, India
Background: Oral cancer, particularly oral squamous cell carcinoma (OSCC), remains a major global health concern, with delayed diagnosis contributing substantially to morbidity and mortality. Conventional clinical examination, imaging and histopathological assessment remain the c [....] » Read More
Title : Novel diagnostic approaches towards RR-TB detection: Advancing the fight against MDR-TB control
Arjun Sankhla, Indian Institute of Technology Kharagpur, India
Tuberculosis (TB) ranks as one of the most widespread infectious diseases in the world due to the fact that multidrug resistant (MDR), extensively resistant (XDR), and totally resistant (TDR) strains are becoming more prevalent. Therefore, in order to curb this widespread, there [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Abdulsada A Rahi Al Ghnaimawi, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Magda Abdulkalek Ali Al Rubaie, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Ali Abdulsada Al Ghnaimawi, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Green synthesis and treatment of silver nanoparticles from Leishmania major in Iraq
Abdulsada A Rahi Al Ghnaimawi, Wasit University, Iraq
Nanoparticles (NPs) play an important role in the diagnosis and treatment of diseases in consequence of their larger surface areas in comparison to the bulk material. Among the variety of nanomaterials, metal nanoparticles (MNPs) present unique physical, chemical and biological p [....] » Read More
Title : Green synthesis and treatment of silver nanoparticles from Leishmania major in Iraq
Magda Abdulkalek Ali Al Rubaie, Wasit University, Iraq
Nanoparticles (NPs) play an important role in the diagnosis and treatment of diseases in consequence of their larger surface areas in comparison to the bulk material. Among the variety of nanomaterials, metal nanoparticles (MNPs) present unique physical, chemical and biological p [....] » Read More
Title : Green synthesis and treatment of silver nanoparticles from Leishmania major in Iraq
Ali Abdulsada Al Ghnaimawi, Wasit University, Iraq
Nanoparticles (NPs) play an important role in the diagnosis and treatment of diseases in consequence of their larger surface areas in comparison to the bulk material. Among the variety of nanomaterials, metal nanoparticles (MNPs) present unique physical, chemical and biological p [....] » Read More