While biofuels, biomass, renewable energy, climate change, and other related topics are popular these days, rarely realistic strategies have been proposed. The favorable economics of petroleum continues to drive global traditional industrial manufacturing and vehicle transportati [....] » Read More
Implant infection is rising with the U.S. Centers for Disease Control predicting one person every three seconds will die from a bacteria infection by 2050. Nanomedicine is the use of nanomaterials to improve disease prevention, detection, and treatment which has resulted in hundr [....] » Read More
The prediction of the evolution of complex dynamic systems from image sequences is a significant challenge in the context of machine learning and data-driven systems, especially in the presence of non-linear dynamics, noise and limited datasets. In this work is presented a deep l [....] » Read More
In biopharmaceutical manufacturing, approximately 60-70% of all recombinant proteins are produced in mammalian cells, with Chinese Hamster Ovary (CHO) cells representing the preferred expression system. Clinical efficacy and safety can be significantly affected by the glycosylati [....] » Read More
We report a novel, multifunctional antimicrobial nanocomposite engineered via a green route from agro-industrial shrimp shell waste, integrating chitosan, in situ synthesized silver nanoparticles (AgNPs), and exfoliated Ti?C?T? MXene. To the best of our knowledge, this is among t [....] » Read More
The release of undesirable dye effluents from most textile industries into the environment constitutes a significant pollution load on the ecosystem. Dyes are recalcitrant to treat, and microbes’ propensity to effectively remove these pollutants and make the environment pol [....] » Read More
The genus Artemisia (Asteraceae)is one of the plants that is widely used as a flavoring and traditional medicine in Asian,European and American countries. Numerous compounds,including essential oils and secondary metabolites such as flavonoids,phenylpropanoids,coumarins, are resp [....] » Read More
Antimicrobial resistance (AMR) is spreading worldwide and poses serious risks to public health. Especially in nations with limited resources where diagnostic capabilities and antibiotic stewardship are often limited. In this study, bacteria were collected from three hospitals in [....] » Read More
Extracellular Vesicles (EVs) are lipid bilayer–enclosed nanoparticles released by virtually all cells and are now recognized as key mediators of intercellular communication. Their capacity to transfer lipids, proteins, nucleic acids, and metabolites has spurred intense inte [....] » Read More
I will review the tangible improvements my colleagues and I have achieved in novel biomarkers across various clinical specialties, and which have led to more accessible, affordable, and accurate diagnostics. Partially, these advances are due to non-trivial computational analyses [....] » Read More
Silk fibroin (SF) and chitosan (CS) are biopolymers widely studied as resorbable scaffolds for regenerative medicine. In this study, SF/CS composite plugs were prepared at 70:30 and 60:40 ratios and compared with single-polymer controls to evaluate their physicochemical propertie [....] » Read More
Weeds outcompete crops for natural resources, reducing productivity (growth, yields) and quality of products. Globally, the annual worth of agrochemicals used to protect crops from weeds is estimated to US$75.3 billion. Blind use of chemicals to maximize production ensuring food [....] » Read More
Despite unprecedented advances in molecular biology, genomics, biomarker discovery, artificial intelligence and translational science, the probability that a drug entering clinical development will ultimately reach patients remains remarkably low. Why do apparently promising mole [....] » Read More
This talk highlights innovative strategies for utilizing microbial systems to produce biofuels, biochemicals, and high-value biomolecules from lignocellulosic biomass and other renewable resources. Key focus areas include microbial fermentation, bioreactor design, enzymatic and b [....] » Read More
Group B Streptococcus (GBS) is a leading cause of neonatal infection, meningitis, and pneumonia, yet existing diagnostic methods are time-consuming or dependent on specialised laboratories, limiting their use for early screening during pregnancy. To address this challenge, we use [....] » Read More
This work introduces a family of fuzzy spherically truncated 3D multilinear descriptors for protein structure representation. The proposed indices encode geometric information derived from k-th order spherically truncated spatial dissimilarity two-tuple and three-tuple tensors. T [....] » Read More
The concept of biostimulants has become firmly established worldwide as a key strategy in modern, sustainable agriculture, aimed at enhancing crop yield and resilience. These tools act as a complement that potentiates natural physiological processes, improving nutrient-use effici [....] » Read More
Introduction: Microbial colony enumeration is central to microbiological testing, including microbial limit testing used in pharmaceutical and consumer safety assessment. Although automated colony counting systems have been proposed, most rely on laboratory-grade images and per [....] » Read More
Health systems and health trends are always changing. Since no health system is flawless, a complement is required. As a result, practitioners of Western medicine (WM) are searching for traditional medicine Ayurveda (TM), and vice versa, since TM is better at treating chron [....] » Read More
Non-small cell lung cancer (NSCLC) remains difficult to treat because nearly half of cases lack targetable mutations and often develop therapy resistance, making epigenetic reprogramming an attractive therapeutic strategy. The current study investigates how Signal Transducer and [....] » Read More
Despite advancements in agriculture and farming over the years, hunger (defined as “an uncomfortable or painful physical sensation caused by insufficient consumption of dietary energy”) continues to increase in some parts of the world. The author of this work argues t [....] » Read More
Environmental biotechnology (EB) implies application of biological systems to solve ecological problems, manage waste, and reduce pollution. Biological systems refer to microorganisms, plants, and enzymes. EB touches upon biochemistry, microbiology, and environmental engineering [....] » Read More
Cancer is a major reason of death worldwide in human beings and traditional chemotherapy is usually connected with poor specificity, systemic toxicity and unwanted side effects. Nanoparticles based targeted drug delivery systems have come out as a favourable approach to overcome [....] » Read More
Rocket propellant contaminants such as unsymmetrical dimethylhydrazine (UDHM) and perchlorate (ClO4?) represent a new group of hazardous pollutants that have emerged due to aerospace applications, military missions, and industrial practices. These contaminants pose significant ec [....] » Read More
Antimicrobial resistance (AMR) is no longer a looming threat - it is an active crisis. The World Health Organization estimates that drug-resistant infections already claim over 1.27 million lives annually, with projections suggesting the toll could reach 10 million per year [....] » Read More
Lignocellulose is the primary structural component of plant cell wall, and Earth’s most abundant renewable organic resource[1,2]. Certain anaerobic bacteria are able to efficiently degrade lignocellulose through cellulosomes, large extracellular multienzyme assemblies with [....] » Read More
The rumen is a highly specialized anaerobic ecosystem in which diverse microbial populations produce enzymes required for the degradation of plant cell wall polysaccharides. Xylan, the major hemicellulosic component of plant biomass, represents a key substrate in this process, an [....] » Read More
Title : Steps and strides: Cross-species insights into movement and injury
Babak Faramarzi, Western University of Health Sciences, United States
Musculoskeletal disorders are a major cause of pain, functional limitation, and reduced quality of life, with increasing prevalence driven by aging, obesity, and physical inactivity. Early and accurate diagnosis remains a persistent clinical challenge, particularly when assessmen [....] » Read More
Title : Process intensification for the continuous production of alternative proteins
Laura Pasitka, GEA Liquid Technologies Germany GmbH, Germany
Optimizing equipment utilization in biotechnological manufacturing systems remains a central challenge during the scale-up transition from laboratory to industrial production. Substantial research and development focus on process intensification and transforming batch and fed-bat [....] » Read More
Title : Novel diagnostic approaches towards RR-TB detection: Advancing the fight against MDR-TB control
Arjun Sankhla, Indian Institute of Technology Kharagpur, India
Tuberculosis (TB) ranks as one of the most widespread infectious diseases in the world due to the fact that multidrug resistant (MDR), extensively resistant (XDR), and totally resistant (TDR) strains are becoming more prevalent. Therefore, in order to curb this widespread, there [....] » Read More
Title : Process parameter optimization for enhancing pigment productivity in chlorella vulgaris
Akanksha Singh, Indian Institute of Technology Kharagpur, India
Microalgae are recognized as promising biofactories for producing a range of industrially valuable and economically significant products. Microalgal cultivation for high-value pigments often suffers from economic bottlenecks due to low productivity under standard conditions. This [....] » Read More
Title : The journey of filamentous fungi and yeasts as natural or heterologous hosts for the production of food colorants
Sameer Ahmed Shamsuddin Mapari, Formerly VIVA College Affiliated to University of Mumbai, India
Recent research has proved that fungal pigments can be produced in high titres in bioreactors under controlled culture conditions unlike plant based food colorants that are seasonal and often produced/extracted in low yields with variable pigment profile. In the past, fungal pigm [....] » Read More
Title : Engineering Sf9 host cells with AcMNPV genes to control baculovirus infection dynamics and heterologous gene expression
Tamer Z Salem, Zewail City of Science and Technology, Egypt
The baculovirus–insect cell expression system is extensively used for recombinant protein production and vaccine development; however, interactions between viral genes and their host cells critically influence infection efficiency, heterologous gene expression, and virus yi [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Abdulsada A Rahi Al Ghnaimawi, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Magda Abdulkalek Ali Al Rubaie, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Production of nanoliposomal amphotericin B 0.4% topical gel as effective treatment for human acne vulgaris
Ali Abdulsada Al Ghnaimawi, Wasit University, Iraq
Acne (also known as acne vulgaris) is a persistent chronic skin inflammatory condition of the pilosebaceous follicles that affects people all over the world. Acne is projected to affect 9.4% of the global population, ranking it eighth among skin diseases. Acne affects more than 8 [....] » Read More
Title : Isolation, characterization, and genetic documentation of rhizosphere microorganisms associated with the medicinal plant Pulicaria undulata in Qatar
Reem Ahmad M A Al Haidose , Ministry of Municipality, Qatar
Background :The rhizosphere is one of the most biologically active soil environments, containing diverse microbial communities that play important roles in plant growth, nutrient availability, and tolerance to environmental stress. This study aims to isolate, characterize, and ge [....] » Read More
Title : Phytochemical composition and health risk assessment of heavy metals in herbal remedies from semi-arid Nigeria
Hajara Momoh, Federal University Kano, Nigeria
Herbal remedies are widely utilized as alternative medicine, especially in Nigeria’s semi-arid regions where medicinal plants are abundant. The study evaluated the phytochemical composition and heavy metal content of Cadmium (Cd), Cobalt (Co), Nickel (Ni), Lead (Pb), and Zi [....] » Read More
Title : Advancement in dual lateral flow immunoassay design for sensitive, rapid detection of rotavirus and adenovirus in stool samples
Ayan Ahmed Isse, Genexus Biotech Company, Somalia
Molecular biotechnology continues to redefine point-of-care diagnostics by integrating advanced biomolecular recognition with nanotechnology-based detection systems. This study presents the development of a Dual Lateral Flow Immuno Assay (DLFIA) for simultaneous detection of rota [....] » Read More
Title : Inducible cellular memory using switchable synthetic plasmid origins of replication
Andrew Gutierrez, University of New Mexico, United States
Control of plasmid replication rate is undertaken by many different cellular mechanisms, enabling compatible plasmids to be stably co-maintained in cells. This capability is essential for a multitude of engineering applications, including metabolic engineering, programmable genet [....] » Read More
Title : A miniaturized electrochemical biosensor for real-time in vivo potassium monitoring in the inner ear
Faezeh Arshadi, Macquarie university, Australia
This work presents a miniaturized potassium-selective biosensor with a solid-state reference electrode, designed for real-time, in vivo monitoring of potassium ion (K?) dynamics in the cochlea. Potassium plays a central role in auditory transduction and mechano-electrical signal [....] » Read More
Title : Unveiling the role of PAR 1: A crucial link with inflammation in Diabetic subjects with COVID-19
Varinder Singh, Prabha Harjilal College of Pharmacy, India
Objectives The aim of the present study is to examine the serum PAR-1 levels and determine their association with different biochemical parameters and inflammatory biomarkers in COVID-19 diabetic patients (T2DM) and non-diabetic COVID 19 patients. Methodology T2DM patients wit [....] » Read More
Title : Revolutionizing diagnostics with biosensors
Anshu Prasad, GSFC University, India
Biosensors represent a remarkable emulsion of biology and technology, acting as" smart" islands that restate complex natural relations into measurable digital data. At their core, these bias use a two- part system a bioreceptor, similar as an enzyme, antibody, or DNA st [....] » Read More