Title: Assessment of faecal carriage of ampc producing e. Coli and klebsiella spp among some students
Abstract:
AmpC-producing organisms can act as a hidden reservoir for ESBLs; the high-level expression of the AmpC β-lactamases may mask the recognition of the ESBLs. In recent years, the world has seen a surge in Enterobacteriaceae resistant to broad-spectrum betalactam antibiotics due to the production of extended-spectrum beta-lactamases (ESBLs) or plasmid-mediated AmpC (pAmpC) enzymes. The aim of this study was to determine faecal carriage of AmpC producing enterobactercae among students of Ambrose Alli University, Ekpoma, Edo State. Fecal samples were collected from 102 students of AAU who accepted to participate in the study, who had not been recently hospitalized and had no recent exposure to antibiotics (≥ 3 months): all are from healthy individuals (students of AAU). Of the 102 faecal samples analysed, 46 were lactose fermenters which were assessed for AmpC. In this current study, the prevalence of fecal carriage of AmpC genes among HCWs was 28.26%. To our knowledge, this is the first study investigating the prevalence of AmpC-producing E. coli isolated from stool samples healthy subjects in this axis. This study demonstrated a prevalence of colonization by multi-drug resistant, non-clonally-related AmpC positive E. coli and Klebsiella spp. Isolates among male and female university students in AAU Ekpoma. Colonization of AmpC in the population of study was not related to prior antimicrobial consumption or hospitalization.
Audience Take Away Notes :
• The prevalence of fecal carriage of AmpC -producing lactose fermenting enterobactercae among the students studied
• The audience will learn and identify the antibiotics sensitivity pattern of isolated lactose fermenting enterobactercae
• This is a research that other faculty could use to expand their research or teaching
• This research will provide a practical solution to a problem that could simplify or make a designer’s job more efficient
