HYBRID EVENT: You can participate in person at Rome, Italy or Virtually from your home or work.

4th Edition of Euro-Global Conference on Biotechnology and Bioengineering

September 19-21 | Hybrid Event

September 19-21, 2024 | Rome, Italy
ECBB 2024

Arjama Mukherjee

Arjama Mukherjee, Speaker at Bioengineering Conferences 2024
Indian Association for the Cultivation of Science (IACS), India
Title: Electrophoretic deposition of fish bone collagen coupled boron nitride on Ti-6A1-4V for osteointegration

Abstract:

The placement of Titanium implants has become an attractive method for the bone regeneration process. However, the poor osteointegration effects lead to poor cellularization which opens the gateway for novel biocompatible coating. Using these findings here in this work we have prepared a novel coating material using hexagonal boron nitride and fishbone collagen. This biocompatible coating can have mechanical strength, antibacterial property, and osteointegration property which can be appropriate for BTE application. Further, the coating of this bioactive aerogel material on a Titanium implant will lead to a successful formation of a smart aerogel implant for bone healing. The preparation and coating of commercially pure titanium samples with collagen-poly(dialdehyde) guar gum conjugated hexagonal boron nitride by electrophoretic deposition for bone tissue engineering applications. The structural characterization, FTIR, XRD, and TGA were used while scanning electron microscopy (SEM) equipped with EDS was done to investigate the morphological characterization. The coating morphology, thickness, and adhesion behavior were studied and proved for developing uniform bioactive coatings of PDAGG-collagen conjugated BN on titanium plate by EPD. Further, this implant leads to an increase in MG-36 fibroblast cell density and proliferation thereby implying its high potential to be used as an implant for bone tissue engineering applications.

Audience Take Away Notes:

  • The placement of Titanium implants has become an attractive method for the bone regeneration process. The electrophoretic deposition has become a very interesting option to coat an implant material used for bone tissue engineering which improves the surface property and bioactivity of the implant
  • We have prepared a novel coating material using hexagonal boron nitride and fishbone collagen. This biocompatible coating can have mechanical strength, antibacterial property, and osteointegration property which can be appropriate for BTE application
  • Our work suggested that the implant is non-toxic, provide good cellularization thereby promising as an effective system for bone tissue engineering applications

Biography:

Dr. Arjama Mukherjee, a Nano-biotechnologist by profession, has graduated as M.Tech in Biotechnology from KIIT University in 2017. She then joined PhD at National Center for Nanoscience and Nanotechnology, University of Madras. She received her PhD degree in 2023 and her thesis entitled “Fabrication of biomaterial based nanogel for breast cancer and orthopedic applications”. Her  research interests include medical biomaterials and their applications, along with cancer biology. She has several international publications with multiple citations in high impact journals to her name. Currently she is working as Post Doctoral Research Associate at Indian Association for the Cultivation of Sciences (IACS), India.

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